SKU: A078  / 
    CAS Number: 90503-06-3

    Azithromycin impurity L, EvoPure®

    ¥1,619.30

    Azithromycin impurity L, EvoPure® (Azithromycin N-Oxide) is one of several impurities found in Azithromycin and can be used as a reference standard for impurity profiling.

    TOKU-E carries the following Azithromycin derivatives:

    ApplicationAzithromycin impurity L can be used as a reference standard. Reference standards are well characterized compounds that can be used to help identify and/or quantify impurities in pharmaceutical compounds and antimicrobials.
    Mechanism of ActionAzithromycin inhibits bacterial growth by binding to the 70S ribosome (specifically the 50S subunit) preventing peptide bond formation and translocation during protein synthesis. Resistance is attributed to mutations in 50S rRNA preventing binding of Azithromycin and allowing the cell to synthesize error-free proteins.
    Molecular FormulaC38H72N2O13
    References

    Gladue RP, Bright GM, Isaacson RE, Newborg MF (1989) In vitro and in vivo uptake of Azithromycin (CP-62,993) by phagocytic cells: Possible mechanism of delivery and release at sites of infection. Antimicrob. Agents Chemother. 33(3):277-282 PMID 2543276

    Lovmar, M and Tenson T (2003) The Mechanism of Action of Macrolides, Lincosamides and Streptogramin B Reveals the Nascent Peptide Exit Path in the Ribosome."Journal of Molecular Microbiology 330 (5):1005-1014. PMID 12860123

    Wolf K and Malinverni R (1999) Effect of Azithromycin plus Rifampin versus that of Azithromycin alone on the eradication of Chlamydia pneumoniae from lung tissue in experimental pneumonitis. Antimicrob. Agents Chemother. 43(6):1491-1493. PMID 10348778

    MICAggregatibacter actinomycetemcomitans| <2 - ?| 821| Bacillus circulans (pH 7.0)| ≤0.03 - >32| 818| Bacillus circulans (pH 8.0)| ≤0.03 - 16| 818| Bacteroides capillosus (pH 7.0)| ≤0.03 - 0.25| 818| Bacteroides capillosus (pH 8.0)| ≤0.03 - 0.25| 818| Bacteroides tectum| 0.5 - 2| 1460| Bacteroides ureolyticus| 0.06 - 0.25| 1460| Bacteroides ureolyticus (pH 7.0)| ≤0.03 - 0.25| 818| Bacteroides ureolyticus (pH 8.0)| ≤0.03 - 0.25| 818| Bifidobacterium breve (pH 7.0)| ≤0.03 - >32| 818| Bifidobacterium breve (pH 8.0)| ≤0.03 - 16| 818| Bifidobacterium longum (pH 7.0)| ≤0.03 - >32| 818| Bifidobacterium longum (pH 8.0)| ≤0.03 - 16| 818| Borrelia afzelii (EB1)| ≤0.015 - ?| 402| Borrelia afzelii (EB1)| 0.0156 - ?| 261| Borrelia afzelii (EB2)| 0.0039 - ?| 261| Borrelia afzelii (FAC-1)| 0.0019 - ?| 261| Borrelia afzelii (FEM1)| 0.0019 - ?| 261| Borrelia afzelii (FEM1)| ≤0.015 - ?| 402| Borrelia afzelii (PKo)| ≤0.015 - ?| 402| Borrelia afzelii (VS461)| 0.0004 - ?| 261| Borrelia bissettii (25015)| 0.0039 - ?| 261| Borrelia bissettii (25015)| <0.015 - ?| 402| Borrelia burgdorferi| ≤0.015 - 0.06| 402| Borrelia burgdorferi| ≤0.001 - ?| 15| Borrelia burgdorferi (297)| ≤0.0002 - ?| 261| Borrelia burgdorferi (ATCC 35210 + B31)| 0.0019 - ?| 261| Borrelia burgdorferi (LW2)| 0.0009 - ?| 261| Borrelia burgdorferi (PKa-I)| 0.0004 - ?| 261| Borrelia burgdorferi (Sensu stricto + B31)| ≤0.015 - ?| 402| Borrelia burgdorferi (Sensu stricto + LW2)| ≤0.015 - ?| 402| Borrelia burgdorferi (Sensu stricto + PKa-I)| ≤0.015 - ?| 402| Borrelia burgdorferi (Z25)| 0.0009 - ?| 261| Borrelia burgdorferi S.L.| 0.003 - 0.3| 1129| Borrelia garinii (A87SB)| 0.0004 - ?| 261| Borrelia garinii (G1)| ≤0.015 - ?| 402| Borrelia garinii (JP2)| 0.0019 - ?| 261| Borrelia garinii (PSth)| ≤0.015 - ?| 402| Borrelia garinii (PSth)| 0.0156 - ?| 261| Borrelia garinii (PTrob)| 0.0009 - ?| 261| Borrelia garinii (PTrob)| ≤0.015 - ?| 402| Borrelia garinii (ZQ1)| 0.0009 - ?| 261| Borrelia valaisiana (VS116)| 0.0009 - ?| 261| Borrelia valaisiana (VS116)| ≤0.015 - ?| 402| Brevibacterium spp.| ≤0.03 - >64| 185| Brevibacterium spp.| 0.03 - >128| 488| Brucella melitensis (pH 5.0)| 16 - >256| 318| Brucella melitensis (pH 7.0)| <0.125 - 4| 318| Campylobacter concisus (pH 7.0)| 0.125 - 0.5| 818| Campylobacter concisus (pH 8.0)| ≤0.03 - 0.5| 818| Campylobacter gracilis (pH 7.0)| 0.125 - 0.5| 818| Campylobacter gracilis (pH 8.0)| ≤0.03 - 0.5| 818| Campylobacter mucosalis (pH 7.0)| 0.125 - 0.5| 818| Campylobacter mucosalis (pH 8.0)| ≤0.03 - 0.5| 818| Campylobacter rectus (pH 7.0)| 0.125 - 0.5| 818| Campylobacter rectus (pH 8.0)| ≤0.03 - 0.5| 818| Campylobacter showae (pH 7.0)| 0.125 - 0.5| 818| Campylobacter showae (pH 8.0)| ≤0.03 - 0.5| 818| Campylobacter spp.| 0.25 - ?| 478| Campylobacter sputorum (pH 7.0)| 0.125 - 0.5| 818| Campylobacter sputorum (pH 8.0)| ≤0.03 - 0.5| 818| Candida (MY 1055)| >32 - ?| 1072| Capnocytophaga ochracea (pH 7.0)| ≤0.03 - 0.25| 818| Capnocytophaga ochracea (pH 8.0)| ≤0.03 - 0.25| 818| Chlamydia pneumonia| 0.015 - 0.5| 950| Chlamydia pneumonia| 0.015 - 0.125| 8| Chlamydia pneumonia| 0.015 - 0.5| 948| Chlamydia pneumonia| 0.062 - 0.125| 170| Chlamydia pneumonia| 0.015 - 0.5| 5| Chlamydia pneumonia (CV-1)| 0.05 - ?| 292| Chlamydia pneumonia (CV-3)| 0.05 - ?| 292| Chlamydia pneumonia (CV-4)| 0.05 - ?| 292| Chlamydia pneumonia (CV-5)| 0.05 - ?| 292| Chlamydia pneumonia (CV-6)| 0.1 - ?| 292| Chlamydia pneumonia (CWL)| 0.1 - ?| 292| Chlamydia pneumonia (IOL-207)| 0.25 - ?| 963| Chlamydia pneumonia (KAjaani-6)| 0.25 - ?| 963| Chlamydia pneumonia (KKpn1)| 0.25 - ?| 963| Chlamydia pneumonia (KKpn15)| 0.25 - ?| 963| Chlamydia pneumonia (KKpn2)| 0.125 - ?| 963| Chlamydia pneumonia (KKpn6)| 0.125 - ?| 963| Chlamydia pneumonia (MUL-1)| 0.1 - ?| 292| Chlamydia pneumonia (TW-183)| 0.125 - ?| 963| Chlamydia pneumonia (TW-183)| 0.125 - ?| 963| Chlamydia trachomatis| 0.062 - 0.125| 170| Chlamydia trachomatis| 0.016 - 0.031| 268| Chlamydophila pneumonia| 0.015 - 0.5| 1113| Chlamydophila pneumonia| ? - ?| 602| Chlamydophila pneumonia| 0.063 - 0.125| 268| Citrobacter koseri| 2 - >8| 1467| Clostridium clostridioforme| 0.125 - >32| 1460| Clostridium difficile| 1 - >32| 1460| Clostridium innocuum| 0.125 - >32| 1460| Clostridium ramosum| 0.125 - >32| 1460| Collinsella aerofaciens (pH 7.0)| ≤0.03 - 0.25| 818| Collinsella aerofaciens (pH 8.0)| ≤0.03 - 0.06| 818| Corynebacterium afermentans| 0.03 - >128| 488| Corynebacterium amycolatum| 0.125 - >64| 185| Corynebacterium amycolatum| 4 - >128| 488| Corynebacterium jeikeium| 0.06 - >64| 185| Corynebacterium jeikeium| 0.06 - >128| 488| Corynebacterium minutissimum| 0.12 - >128| 488| Corynebacterium minutissimum| ≤0.03 - >64 185| Corynebacterium pseudodiphtheriticum| ≤0.015 - >128| 488| Corynebacterium spp.| 0.03 - >128| 5| Corynebacterium striatum| >64 - ?| 185| Corynebacterium striatum| 0.03 - >128| 488| Corynebacterium urealyticum| ≤0.015 - >128| 488| Corynebacterium urealyticum| 0.5 - >64| 185| Coryneform (CDC group I6)| 0.03 - >128| 488| Dialister pneumosintes (pH 7.0)| ≤0.03 - 0.25| 818| Dialister pneumosintes (pH 8.0)| ≤0.03 - 0.25| 818| Edwardsiella ictaluri| 0.5 - 32| 1409| Eikenella corrodens| ≤0.5 - >4| 144| Eikenella corrodens (pH 8.0)| 0.25 - 2| 818| Enterobacteriaceae| 0.25 - 128| 401| Enterococcus (erythromycin A-resistant)| 64 - >=512| 271| Enterococcus (erythromycin A-susceptible)| 0.06 - 64| 271| Enterococcus (penicillin-resistant)| 2 - >=512| 271| Enterococcus (penicillin-susceptible)| 0.06 - >=512| 271| Enterococcus (van(A))| ≥512 - ?| 271| Enterococcus faecalis (CL 5246 + vancomycin-resistant)| >32 - ?| 1072| Enterococcus faecalis (CL 8516 + vancomycin-susceptible)| >32 - ?| 1072| Enterococcus faecalis (Periapical lesions)| 2 - >256| 407| Enterococcus faecalis (vancomycin-resistant)| 8 - >32| 948| Enterococcus faecalis (vancomycin-resistant)| >8 - ?| 496| Enterococcus faecalis (vancomycin-susceptible)| 2 - >8| 948| Enterococcus faecalis (vancomycin-susceptible)| 2 - >8| 496| Enterococcus faecium (CL 8145 + vancomycin-susceptible)| >32 - ?| 1072| Enterococcus faecium (CL 8450 + vancomycin-resistant)| >32 - ?| 1072| Enterococcus faecium (vancomycin-resistant)| >8 - ?| 948| Enterococcus faecium (vancomycin-resistant)| >8 - ?| 496| Enterococcus faecium (vancomycin-resistant)| ? - ?| 602| Enterococcus faecium (vancomycin-susceptible)| 0.25 - >8| 496| Enterococcus faecium (vancomycin-susceptible)| 0.25 - >8| 948| Enterococcus faecium (vancomycin-susceptible)| ? - ?| 602| Enterococcus spp.| 0.25 - >8| 496| Enterococcus spp. (macrolide-resistant)| >128 - ?| 15| Enterococcus spp. (macrolide-susceptible)| 0.25 - 2| 15| Erysipelothrix rhusiopathiae| 0.03 - ?| 488| Escherichia coli| 1 - 512| 946| Escherichia coli (250 UC5)| 20 - ?| 58| Escherichia coli (enteroaggregative)| ≤0.0156 - ?| 478| Escherichia coli (enterotoxigenic)| ≤0.0156 - ?| 478| Escherichia coli (MB 2884)| >32 - ?| 1072| Escherichia coli (MB 5431 + tetracycline-resistant)| 2 - ?| 1072| Escherichia coli (MCR106)| 1 - ?| 794| Escherichia coli (OC1555)| 160 - ?| 794| Escherichia coli (PLB3255)| 80 - ?| 794| Escherichia coli (RAM121)| 3.2 - ?| 794| Escherichia coli (RAM122)| 1.6 - ?| 794| Eubacterium lentum (pH 7.0)| ≤0.03 - 0.25| 818| Eubacterium lentum (pH 8.0)| ≤0.03 - 0.06| 818| Eubacterium saburreum (pH 7.0)| ≤0.03 - 0.125| 818| Eubacterium saburreum (pH 8.0)| ≤0.03 - <=0.03| 818| Eubacterium spp. (pH 7.0)| ≤0.03 - 0.25| 818| Eubacterium spp. (pH 8.0)| ≤0.03 - 0.06| 818| Eubacterium timidum (pH 7.0)| ≤0.03 - 0.25| 818| Eubacterium timidum (pH 8.0)| ≤0.03 - 0.06| 818| Eubacterium yurii (pH 7.0)| ≤0.03 - 0.25| 818| Eubacterium yurii (pH 8.0)| ≤0.03 - 0.06| 818| Finegoldia magna (pH 7.0)| ≤0.03 - >32| 818| Finegoldia magna (pH 8.0)| ≤0.03 - 32| 818| Fusobacterium gonidiaformans| 0.06 - 32| 1460| Fusobacterium mortiferum| 1 - >32| 1460| Fusobacterium naviforme| 0.06 - 32| 1460| Fusobacterium naviforme (pH 7.0)| 0.125 - 1| 818| Fusobacterium naviforme (pH 8.0)| ≤0.03 - 1| 818| Fusobacterium necrogenes| 1 - >32| 1460| Fusobacterium necrophorum| 0.06 - 32| 1460| Fusobacterium necrophorum (pH 7.0)| 0.125 - 1| 818| Fusobacterium necrophorum (pH 8.0)| ≤0.03 - 1| 818| Fusobacterium nucleatum| 0.06 - 32| 1460| Fusobacterium nucleatum| 2 - >64| 821| Fusobacterium nucleatum (pH 7.0)| ≤0.03 - 2| 818| Fusobacterium nucleatum (pH 8.0)| ≤0.03 - 1| 818| Fusobacterium nucleatum subsp. animalis| 0.06 - 32| 1460| Fusobacterium russii| 0.03 - 32| 1460| Fusobacterium ulcerans| 1 - >32| 1460| Fusobacterium varium| 2 - >32| 1460| Haemophilus influenzae| 0.25 - 2| 15| Haemophilus influenzae| ≤0.06 - >16| 412| Haemophilus influenzae| 0.25 - 32| 499| Haemophilus influenzae| 0.5 - 8| 1113| Haemophilus influenzae| 0.015 - >128| 1113| Haemophilus influenzae| 0.12 - 4| 125| Haemophilus influenzae| ≤0.12 - >16| 500| Haemophilus influenzae| 0.001 - >=64| 950| Haemophilus influenzae| <0.01 - 8| 948| Haemophilus influenzae| ? - ?| 602| Haemophilus influenzae| ? - ?| 1044| Haemophilus influenzae (351HT3)| 1.2 - ?| 58| Haemophilus influenzae (ampicillin-resistant + β-lactamase negative)| ≤0.5 - 4| 462| Haemophilus influenzae (ampicillin-resistant)| ? - ?| 58| Haemophilus influenzae (ampicillin-susceptible)| ? - ?| 58| Haemophilus influenzae (ATCC 49247)| 2 - ?| 401| Haemophilus influenzae (azithromycin-susceptible)| ≤4 - ?| 452| Haemophilus influenzae (ciprofloxacin-susceptible)| 0.12 - 2| 1467| Haemophilus influenzae (ESBL + ampicillin-resistant)| 0.12 - 2| 18| Haemophilus influenzae (ESBL + ampicillin-resistant)| 0.12 - 4| 18| Haemophilus influenzae (ESBL + ampicillin-susceptible)| 0.12 - 4| 18| Haemophilus influenzae (ESBL)| ≤0.25 - >8| 499| Haemophilus influenzae (ESBL)| 0.5 - 4| 195| Haemophilus influenzae (ESBL)| <0.12 - >256| 45| Haemophilus influenzae (ESBL)| 0.25 - 64| 45| Haemophilus influenzae (HTM)| 0.5 - 8| 134| Haemophilus influenzae (NCTC 11931)| 2 - ?| 401| Haemophilus influenzae (non-ESBL)| 0.25 - >32| 195| Haemophilus influenzae (non-ESBL)| ≤0.25 - >32| 499| Haemophilus influenzae (β-lactamase negative)| 0.5 - 4| 462| Haemophilus influenzae (β-lactamase positive)| ≤0.5 - 2| 462| Haemophilus influenzae (β-lactamase positive)| ≤0.12 - 128| 1105| Haemophilus influenzae acr (β-lactamase negative)| ≤0.12 - >256| 1105| Helicobacter pylori (macrolide-resistant)| 128 - >128| 15| Helicobacter pylori (macrolide-susceptible)| 0.06 - 0.5| 15| Klebsiella oxytoca| 8 - >8| 1467| Lactobacillus catenaforme (pH 7.0)| ≤0.03 - >32| 818| Lactobacillus catenaforme (pH 8.0)| ≤0.03 - 16| 818| Lactobacillus delbrueckii (pH 7.0)| ≤0.03 - >32| 818| Lactobacillus delbrueckii (pH 8.0)| ≤0.03 - 16| 818| Lactobacillus oris (pH 7.0)| ≤0.03 - >32| 818| Lactobacillus oris (pH 8.0)| ≤0.03 - 16| 818| Lactobacillus plantarum (pH 7.0)| ≤0.03 - >32| 818| Lactobacillus plantarum (pH 8.0)| ≤0.03 - 16| 818| Lactobacillus spp. (pH 7.0)| ≤0.03 - >32| 818| Lactobacillus spp. (pH 8.0)| ≤0.03 - 16| 818| Legionella pneumophila| 0.008 - 0.125| 963| Legionella pneumophila| 0.008 - 1| 268| Legionella pneumophila| 0.03 - 1| 1467| Legionella pneumophila| <0.06 - 2| 948| Legionella pneumophila| 0.03 - 2| 950| Legionella pneumophila| 0.03 - 2| 1113| Legionella pneumophila| ? - ?| 602| Legionella spp.| 0.12 - 2| 15| Leptotrichia buccalis (pH 7.0)| 0.125 - 1| 818| Leptotrichia buccalis (pH 8.0)| ≤0.03 - 1| 818| Listeria monocytogenes| 0.25 - 1| 1467| Listeria monocytogenes| 0.125 - 2| 185| Listeria monocytogenes| 1 - ?| 15| Listeria spp.| 0.25 - 1| 488| Micromonas micros (pH 7.0)| 0.125 - 0.5| 818| Micromonas micros (pH 8.0)| ≤0.03 - 0.25| 818| Moraxella catarrhalis| ≤0.008 - 0.03| 120| Moraxella catarrhalis| 0.015 - 0.06| 1467| Moraxella catarrhalis| 0.015 - 0.06| 15| Moraxella catarrhalis| 0.015 - 0.12| 86| Moraxella catarrhalis| 0.008 - 8| 1113| Moraxella catarrhalis| 0.008 - >=64| 950| Moraxella catarrhalis| ≤0.015 - 0.12| 195| Moraxella catarrhalis| <0.015 - 0.125| 948| Moraxella catarrhalis| ≤0.015 - 0.5| 125| Moraxella catarrhalis| ≤0.12 - 0.25| 500| Moraxella catarrhalis| ≤0.12 - 0.5| 499| Moraxella catarrhalis| ≤0.12 - 1| 412| Moraxella catarrhalis| ? - ?| 403| Moraxella catarrhalis| ? - ?| 602| Moraxella catarrhalis (ESBL)| 0.03 - 0.25| 45| Moraxella catarrhalis (ESBL)| 0.06 - 0.25| 45| Moraxella catarrhalis (HTM)| 0.06 - 0.125| 134| Moraxella catarrhalis (MHF)| 0.06 - 0.125| 134| Morganella morganii| 8 - >8| 1467| Mycobacterium abscessus| 0.5 - >64| 291| Mycobacterium avium (ATCC 49601)| ? - ?| 87| Mycobacterium avium (macrolide-resistant)| >256 - ?| 15| Mycobacterium avium (macrolide-susceptible)| 16 - >256| 15| Mycobacterium avium complex| 4 - ?| 87| Mycobacterium avium complex (MAC 101c)| 4 - ?| 87| Mycobacterium chelonae| 0.25 - 4| 291| Mycobacterium fortuitum| 1 - >64| 291| Mycobacterium fortuitum| 64 - ?| 87| Mycobacterium malmoense| 16 - ?| 87| Mycobacterium mucogenicum| 0.12 - 1| 291| Mycobacterium peregrinum| 0.5 - 4| 291| Mycobacterium simiae| 4 - ?| 87| Mycobacterium xenopi| 1 - ?| 87| Mycoplasma genitalium| ≤0.015 - 0.03| 31| Mycoplasma genitalium| ≤0.03 - ?| 958| Mycoplasma hominis| 32 - >64| 31| Mycoplasma hominis| 32 - >64| 958| Mycoplasma hominis| >4 - ?| 1006| Mycoplasma hyopneumoniae (F18)| 0.0625 - ?| 761| Mycoplasma hyopneumoniae (F19)| >64 - ?| 761| Mycoplasma hyopneumoniae (F2)| 0.125 - ?| 761| Mycoplasma hyopneumoniae (F5)| 0.125 - 0.25| 761| Mycoplasma hyopneumoniae (F6)| 0.0625 - 0.125| 761| Mycoplasma hyopneumoniae (J-strain)| 0.25 - ?| 761| Mycoplasma penetrans| 0.12 - 0.5| 958| Mycoplasma penetrans| 0.12 - 0.5| 31| Mycoplasma pneumonia| 0.0006 - 0.00048| 948| Mycoplasma pneumonia| ≤0.001 - 0.03| 950| Mycoplasma pneumonia| 0.001 - 0.03| 1113| Mycoplasma pneumonia| ≤0.001 - ?| 139| Mycoplasma pneumonia| ≤0.001 - ?| 182| Mycoplasma pneumonia| ≤0.015 - ?| 958| Mycoplasma pneumonia| ≤0.015 - ?| 31| Mycoplasma pneumonia| 0.062 - 0.25| 81| Mycoplasma pneumonia| ? - ?| 602| Mycoplasma pneumonia| ≤0.0005 - ?| 15| Mycoplasma pneumonia| ≤0.004 - 0.03| 268| Neisseria cinerea| 0.5 - 4| 86| Neisseria meningitidis| <=0.03 - 0.12| 1467| Neisseria meningitidis| 0.25 - 2| 86| Neisseria meningitidis| 0.25 - 2| 948| Neisseria mucosa| 0.06 - 8| 86| Neisseria perflava/sicca| 0.25 - 4| 86| Neisseria polysaccharea| 0.03 - 0.25| 86| Oerskovia spp.| 0.03 - >128| 488| Olsenella uli (pH 7.0)| ≤0.03 - >32| 818| Olsenella uli (pH 8.0)| ≤0.03 - 16| 818| Pasteurella multocida| 0.05 - ?| 63| Peptostreptococcus anaerobius (pH 7.0)| ≤0.03 - >32| 818| Peptostreptococcus anaerobius (pH 8.0)| ≤0.03 - 32| 818| Peptostreptococcus asaccharolyticus| 0.5 - >32| 1460| Peptostreptococcus magnus| 2 - >32| 1460| Peptostreptococcus micros| 0.5 - 1| 1460| Peptostreptococcus prevotii| 0.06 - >32| 1460| Porphyromonas asaccharolytica| 0.125 - >32| 1460| Porphyromonas cangingivalis| 0.125 - 1| 1460| Porphyromonas canoris| 0.125 - 0.5| 1460| Porphyromonas cansulci| 0.125 - 1| 1460| Porphyromonas circumdentaria| 0.125 - 1| 1460| Porphyromonas endodontalis (pH 7.0)| ≤0.03 - 0.25| 818| Porphyromonas endodontalis (pH 8.0)| ≤0.03 - 0.25| 818| Porphyromonas gingivalis| 0.125 - 1| 1460| Porphyromonas gingivalis| <1 - 8| 821| Porphyromonas gingivalis (pH 7.0)| ≤0.03 - 0.25| 818| Porphyromonas gingivalis (pH 8.0)| ≤0.03 - 0.25| 818| Porphyromonas levii| 0.125 - 1| 1460| Porphyromonas macacae| 0.125 - 1| 1460| Prevotella bivia| 0.25 - >32| 1460| Prevotella buccae| 0.125 - 4| 1460| Prevotella buccae (pH 7.0)| 0.06 - >32| 818| Prevotella buccae (pH 8.0)| ≤0.03 - >32| 818| Prevotella buccalis (pH 7.0)| 0.06 - >32| 818| Prevotella buccalis (pH 8.0)| ≤0.03 - >32| 818| Prevotella corporis (pH 7.0)| ≤0.03 - 0.06| 818| Prevotella corporis (pH 7.0)| ≤0.03 - 8| 818| Prevotella corporis (pH 8.0)| ≤0.03 - <=0.03| 818| Prevotella corporis (pH 8.0)| ≤0.03 - 4| 818| Prevotella dentalis (pH 7.0)| 0.06 - >32| 818| Prevotella dentalis (pH 8.0)| ≤0.03 - >32| 818| Prevotella denticola| 0.06 - >32| 1460| Prevotella denticola (pH 7.0)| ≤0.03 - 0.06| 818| Prevotella denticola (pH 7.0)| ≤0.03 - 8| 818| Prevotella denticola (pH 8.0)| ≤0.03 - <=0.03| 818| Prevotella denticola (pH 8.0)| ≤0.03 - 4| 818| Prevotella disiens (pH 7.0)| 0.06 - >32| 818| Prevotella disiens (pH 8.0)| ≤0.03 - >32| 818| Prevotella heparinolytica| 0.5 - 1| 1460| Prevotella intermedia| 0.03 - 1| 1460| Prevotella intermedia| <1 - 4| 821| Prevotella intermedia (pH 7.0)| 0.06 - >32| 818| Prevotella intermedia (pH 8.0)| ≤0.03 - >32| 818| Prevotella loescheii| 0.06 - >32| 1460| Prevotella loescheii (pH 7.0)| ≤0.03 - 0.06| 818| Prevotella loescheii (pH 7.0)| ≤0.03 - 8| 818| Prevotella loescheii (pH 8.0)| ≤0.03 - <=0.03| 818| Prevotella loescheii (pH 8.0)| ≤0.03 - 4| 818| Prevotella melaninogenica| 0.06 - >32| 1460| Prevotella melaninogenica (pH 7.0)| ≤0.03 - 0.06| 818| Prevotella melaninogenica (pH 7.0)| ≤0.03 - 8| 818| Prevotella melaninogenica (pH 8.0)| ≤0.03 - <=0.03| 818| Prevotella melaninogenica (pH 8.0)| ≤0.03 - 4| 818| Prevotella nigrescens (pH 7.0)| 0.06 - >32| 818| Prevotella nigrescens (pH 8.0)| ≤0.03 - >32| 818| Prevotella oralis (pH 7.0)| 0.06 - >32| 818| Prevotella oralis (pH 8.0)| ≤0.03 - >32| 818| Prevotella oris| 0.125 - 4| 1460| Prevotella oris (pH 7.0)| 0.06 - >32| 818| Prevotella oris (pH 8.0)| ≤0.03 - >32| 818| Prevotella pallens (pH 7.0)| 0.06 - >32| 818| Prevotella pallens (pH 8.0)| ≤0.03 - >32| 818| Prevotella spp. (pH 7.0)| 0.06 - >32| 818| Prevotella spp. (pH 8.0)| ≤0.03 - >32| 818| Prevotella tannerae (pH 7.0)| ≤0.03 - 0.06| 818| Prevotella tannerae (pH 7.0)| ≤0.03 - 8| 818| Prevotella tannerae (pH 8.0)| ≤0.03 - <=0.03| 818| Prevotella tannerae (pH 8.0)| ≤0.03 - 4| 818| Prevotella zooglioformans (pH 7.0)| 0.06 - >32| 818| Prevotella zooglioformans (pH 8.0)| ≤0.03 - >32| 818| Propionibacterium avidum (pH 7.0)| ≤0.03 - >32| 818| Propionibacterium avidum (pH 8.0)| ≤0.03 - 16| 818| Pseudomonas aeruginosa (PA01 + reference strain)| 125 - ?| 238| Pseudomonas aeruginosa (PYOA + tobramycin-resistant)| 2000 - ?| 238| Pseudomonas aeruginosa (PYOB + mucoid phenotype)| 1000 - ?| 238| Pseudomonas aeruginosa (PYOC)| 1000 - ?| 238| Pseudomonas aeruginosa (PYOD)| 1000 - ?| 238| Rhodococcus equi| 0.03 - 2| 488| Rhodococcus equi (33701 + Sensititre Plate)| 0.06 - 2| 1042| Rhodococcus equi (33702 + Broth Dilution)| 0.5 - ?| 1042| Rhodococcus equi (macrolide-resistant + 48h)| >4 - ?| 1042| Rhodococcus equi (macrolide-resistant)| >4 - ?| 1042| Rhodococcus equi (macrolide-susceptible)| ≤0.06 - 2| 1042| Salmonella spp.| 1 - ?| 478| Selenomonas flueggei (pH 7.0)| ≤0.03 - 0.25| 818| Selenomonas flueggei (pH 8.0)| ≤0.03 - 0.25| 818| Selenomonas infelix (pH 7.0)| ≤0.03 - 0.25| 818| Selenomonas infelix (pH 8.0)| ≤0.03 - 0.25| 818| Selenomonas spp. (pH 7.0)| ≤0.03 - 0.25| 818| Selenomonas spp. (pH 8.0)| ≤0.03 - 0.25| 818| Shigella spp.| 0.5 - ?| 478| Staphylococci (coagulase-negative)| 0.06 - >=64| 950| Staphylococcus (constitutively erythromycin-resistant)| ? - ?| 58| Staphylococcus (inducibly erythromycin-resistant)| ? - ?| 58| Staphylococcus aureus| 0.25 - >=64| 950| Staphylococcus aureus (011CB20 + constitutively erythromycin-resistant)| 40 - ?| 58| Staphylococcus aureus (011GO25i + inducibly erythromycin-resistant)| 40 - ?| 58| Staphylococcus aureus (011UC4 + erythromycin-susceptible)| 0.3 - ?| 58| Staphylococcus aureus (030CR18c + constitutively erythromycin-resistant)| 40 - ?| 58| Staphylococcus aureus (030PW23c + constitutively erythromycin-resistant)| 40 - ?| 58| Staphylococcus aureus (030SJ5i + inducibly erythromycin-resistant)| 40 - ?| 58| Staphylococcus aureus (032UC1 + erythromycin-susceptible)| 0.15 - ?| 58| Staphylococcus aureus (10649 + erythromycin-susceptible)| 0.78 - ?| 319| Staphylococcus aureus (31593)| 1 - ?| 215| Staphylococcus aureus (ATCC 25923)| 0.12 - ?| 401| Staphylococcus aureus (ATCC 29213)| 0.12 - ?| 401| Staphylococcus aureus (ATCC 29213)| 1 - ?| 215| Staphylococcus aureus (ATCC 29213)| 1 - ?| 1042| Staphylococcus aureus (ATCC 6571)| 0.12 - ?| 401| Staphylococcus aureus (azithromycin-intermediate)| 4 - ?| 452| Staphylococcus aureus (azithromycin-resistant)| ≥8 - ?| 452| Staphylococcus aureus (azithromycin-susceptible)| ≤2 - ?| 452| Staphylococcus aureus (ciprofloxacin-susceptible + methicillin-resistant)| 0.5 - >8| 1467| Staphylococcus aureus (CL 10197 + tetracycline-resistant)| >32 - ?| 1072| Staphylococcus aureus (CL 11821 + methicillin-resistant + tetracycline-resistant)| 4 - ?| 1072| Staphylococcus aureus (CL 14050)| >32 - ?| 1072| Staphylococcus aureus (CL 8072 + methicillin-resistant)| >32 - ?| 1072| Staphylococcus aureus (CL 8949 + tetracycline-resistant)| >32 - ?| 1072| Staphylococcus aureus (CL 9032 + macrolide-resistant + quinolone-resistant)| >32 - ?| 1072| Staphylococcus aureus (CL 9080 + methicillin-susceptible)| 4 - ?| 1072| Staphylococcus aureus (CL 9656 + tetracycline-resistant)| 4 - ?| 1072| Staphylococcus aureus (CL 9689A + tetracycline-resistant + ciprofloxacin-resistant)| >32 - ?| 1072| Staphylococcus aureus (CL 9959 + methicillin-susceptible)| 4 - ?| 1072| Staphylococcus aureus (COL + methicillin-resistant)| 4 - ?| 1072| Staphylococcus aureus (community-acquired + methicillin-resistant)| ? - ?| 602| Staphylococcus aureus (constitutively erm(A) + constitutively erm(C))| >128 - ?| 15| Staphylococcus aureus (constitutively erm(A) + constitutively erm(C))| >128 - ?| 1113| Staphylococcus aureus (erm(A)-inducible)| 16 - >128| 1113| Staphylococcus aureus (erythromycin A-resistant)| 0.5 - >=64| 950| Staphylococcus aureus (erythromycin A-susceptible)| 0.25 - >=16| 950| Staphylococcus aureus (erythromycin-susceptible)| 0.12 - 4| 1113| Staphylococcus aureus (inducible erm(A))| 8 - >128| 15| Staphylococcus aureus (macrolide-susceptible)| 0.25 - 1| 15| Staphylococcus aureus (methicillin-resistant + mupirocin-resistant)| 64 - >64| 120| Staphylococcus aureus (methicillin-resistant)| 0.5 - 128| 948| Staphylococcus aureus (methicillin-resistant)| 1 - >64| 120| Staphylococcus aureus (methicillin-resistant)| ? - ?| 452| Staphylococcus aureus (methicillin-resistant)| ? - ?| 602| Staphylococcus aureus (methicillin-susceptible)| 0.25 - >64| 120| Staphylococcus aureus (methicillin-susceptible)| 0.25 - 64| 948| Staphylococcus aureus (methicillin-susceptible)| ? - ?| 602| Staphylococcus aureus (methicillin-susceptible)| ? - ?| 452| Staphylococcus aureus (msr(A))| 8 - >16| 1113| Staphylococcus aureus (oxacillin-resistant)| 2 - >8| 496| Staphylococcus aureus (oxacillin-susceptible)| ? - ?| 403| Staphylococcus aureus (oxacillin-susceptible)| 1 - >8| 496| Staphylococcus aureus (SJ0301 + constitutively erythromycin-resistant)| 40 - ?| 58| Staphylococcus epidermidis| 0.25 - >64| 120| Staphylococcus epidermidis (ciprofloxacin-susceptible + methicillin-resistant)| 0.25 - >8| 1467| Staphylococcus epidermidis (constitutively MLSB)| >128 - ?| 15| Staphylococcus epidermidis (macrolide-susceptible)| <0.12 - 1| 15| Staphylococcus epidermidis (oxacillin-resistant)| 4 - >8| 496| Staphylococcus epidermidis (oxacillin-susceptible)| 0.5 - >8| 496| Staphylococcus haemolyticus| 0.25 - >8| 1467| Staphylococcus haemolyticus (oxacillin-resistant)| 1 - >8| 496| Staphylococcus haemolyticus (oxacillin-susceptible)| 0.5 - >8| 496| Staphylococcus hominis| 0.12 - >8| 1467| Staphylococcus lugdunensis| 0.25 - >8| 1467| Staphylococcus pneumonia| ? - ?| 602| Staphylococcus pneumonia (penicillin-resistant)| ? - ?| 602| Staphylococcus saprophyticus| 0.12 - >8| 1467| Staphylococcus saprophyticus| 0.25 - >64| 120| Staphylococcus spp. (CL 12557 + coagulase-negative)| 2 - ?| 1072| Staphylococcus spp. (CL 12771 + coagulase-negative + methicillin-susceptible)| 2 - ?| 1072| Staphylococcus spp. (CL 14084 + coagulase-negative + methicillin-resistant + macrolide-resistant)| >32 - ?| 1072| Staphylococcus spp. (CL 8040 + coagulase-negative + methicillin-resistant)| 1 - ?| 1072| Staphylococcus spp. (CL 8341 + coagulase-negative)| >32 - ?| 1072| Staphylococcus spp. (CL 8520 + coagulase-negative + methicillin-resistant + tetracycline-resistant)| >32 - ?| 1072| Staphylococcus spp. (CL 8638 + coagulase-negative + tetracycline-resistant)| >32 - ?| 1072| Staphylococcus spp. (CL 8952 + coagulase-negative + methicillin-resistant)| >32 - ?| 1072| Staphylococcus spp. (coagulase negative)| ? - ?| 603| Staphylococcus spp. (coagulase-negative)| 0.5 - >8| 496| Staphylococcus warneri| 0.12 - >8| 1467| Streptococci (serogroup A)| <0.01 - >256| 948| Streptococci (Viridans group)| ≤0.008 - >8| 120| Streptococci (Viridans group)| 0.008 - >=64| 950| Streptococcus (erythromycin-resistant)| ? - ?| 58| Streptococcus (group C + erythromycin-susceptible)| 0.063 - 0.25| 502| Streptococcus (group G + erythromycin-susceptible)| 0.125 - 1| 502| Streptococcus (group G + inducible erm(TR))| 4 - >64| 502| Streptococcus agalactiae| 0.016 - 4| 120| Streptococcus agalactiae| 0.008 - >=32| 950| Streptococcus agalactiae| 0.015 - >8| 1467| Streptococcus agalactiae (erythromycin-resistant)| 1 - >64| 35| Streptococcus agalactiae (erythromycin-susceptible)| 0.03 - 0.3| 35| Streptococcus anginosus| 0.008 - >8| 1467| Streptococcus bovis| 0.008 - >8| 1467| Streptococcus constellatus| 0.008 - >8| 1467| Streptococcus intermedius| 0.008 - >8| 1467| Streptococcus mitis| 0.008 - >8| 1467| Streptococcus oralis| 0.008 - >8| 1467| Streptococcus pneumonia| 0.016 - >8| 120| Streptococcus pneumonia| ≤0.12 - >16| 499| Streptococcus pneumonia| 0.008 - >=64| 950| Streptococcus pneumonia| 0.031 - 64| 121| Streptococcus pneumonia| ? - ?| 1044| Streptococcus pneumonia (1999-2000)| ≤0.03 - >=128| 275| Streptococcus pneumonia (2000-2001)| ≤0.03 - >=128| 275| Streptococcus pneumonia (2001-2002)| ≤0.03 - >=128| 275| Streptococcus pneumonia (2002-2003)| ≤0.03 - >=128| 275| Streptococcus pneumonia (6396 + MLSB-resistant)| >128 - ?| 319| Streptococcus pneumonia (ATCC 49619)| 0.12 - ?| 401| Streptococcus pneumonia (ATCC 49619)| 0.25 - ?| 1072| Streptococcus pneumonia (ATCC 5649 + efflux-resistant)| 16 - ?| 319| Streptococcus pneumonia (ATCC 6303 + erythromycin-susceptible)| 0.12 - ?| 319| Streptococcus pneumonia (ATCC 6303 + erythromycin-susceptible)| 0.12 - ?| 319| Streptococcus pneumonia (azithromycin-intermediate)| 1 - ?| 452| Streptococcus pneumonia (azithromycin-resistant)| ≥2 - ?| 452| Streptococcus pneumonia (azithromycin-susceptible)| ≤0.05 - ?| 452| Streptococcus pneumonia (CL 14101 + erythromycin-susceptible + penicillin-resistant)| 0.12 - ?| 1072| Streptococcus pneumonia (CL 5771 + penicillin-resistant)| >32 - ?| 1072| Streptococcus pneumonia (CL 8002 + erythromycin-resistant)| 32 - ?| 1072| Streptococcus pneumonia (constitutively erm(B))| >64 - ?| 502| Streptococcus pneumonia (erm(AM))| 1 - >32| 815| Streptococcus pneumonia (erm(B))| 1 - >=64| 950| Streptococcus pneumonia (erm(B))| 4 - >512| 1113| Streptococcus pneumonia (erm(B))| 32 - >64| 1113| Streptococcus pneumonia (erm(B))| 4 - >128| 1111| Streptococcus pneumonia (erm(B))| 4 - >128| 15| Streptococcus pneumonia (erythromycin A-resistant)| ≤0.12 - 32| 499| Streptococcus pneumonia (erythromycin A-susceptible)| 0.008 - 64| 950| Streptococcus pneumonia (erythromycin A-susceptible)| ≤0.12 - 32| 499| Streptococcus pneumonia (erythromycin-resistant + 2000-2001)| 1250 - >256| 369| Streptococcus pneumonia (erythromycin-resistant + 2001-2002)| 0.5 - >256| 369| Streptococcus pneumonia (erythromycin-resistant + 2002-2003)| 128 - >256| 369| Streptococcus pneumonia (erythromycin-resistant + 2003-2004)| 1 - >256| 369| Streptococcus pneumonia (erythromycin-resistant)| 0.03 - 128| 948| Streptococcus pneumonia (erythromycin-resistant)| 1 - >64| 35| Streptococcus pneumonia (erythromycin-resistant)| 0.5 - >256| 1105| Streptococcus pneumonia (erythromycin-susceptible)| 0.03 - 0.125| 1113| Streptococcus pneumonia (erythromycin-susceptible)| 0.008 - 0.25| 1113| Streptococcus pneumonia (erythromycin-susceptible)| 0.03 - 64| 948| Streptococcus pneumonia (erythromycin-susceptible)| ≤0.031 - 0.125| 502| Streptococcus pneumonia (L22 & 23S rRNA mutants)| 0.125 - >64| 1113| Streptococc