• Azithromycin impurity I, EvoPure packaged and labeled.

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SKU: A081

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Description

Azithromycin impurity I, EvoPure® (3'-N-demethylazithromycin) is one of several impurities found in Azithromycin and can be used as a reference standard for impurity profiling.

TOKU-E carries the following Azithromycin derivatives:

    CAS Number

    172617-84-4

    Molecular Formula

    C37H70N2O12

    Molecular Weight

    734.96

    Storage Conditions

    -20°C

    Tariff Code

    2941.50.0000

Applications

    Application

    Azithromycin impurity I is primarily used as a reference standard. Reference standards are well characterized compounds that can be used to help identify and/or quantify impurities in pharmaceutical compounds and antimicrobials.

Specifications

    Appearance

    White powder

    pH

    8-9

    Melting Point

    126.7-127.7°C

Technical Data

HPLC, NMR, FTIR, and MS analysis may be available. For more info, please email [email protected].

References

    References

    Gladue RP, Bright GM, Isaacson RE, Newborg MF (1989) In vitro and in vivo uptake of Azithromycin (CP-62,993) by phagocytic cells: Possible mechanism of delivery and release at sites of infection. Antimicrob. Agents Chemother. 33(3):277-282 PMID 2543276

    Lovmar, M and Tenson T (2003) The Mechanism of Action of Macrolides, Lincosamides and Streptogramin B Reveals the Nascent Peptide Exit Path in the Ribosome."Journal of Molecular Microbiology 330 (5):1005-1014. PMID 12860123

    Wolf K and Malinverni R (1999) Effect of Azithromycin plus Rifampin versus that of Azithromycin alone on the eradication of Chlamydia pneumoniae from lung tissue in experimental pneumonitis. Antimicrob. Agents Chemother. 43(6):1491-1493. PMID 10348778

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