Demethylbleomycin A2 Sulfate, EvoPure® (Bleomycin impurity D) is a demethylated form of Bleomycin A2 - a major component in standard grade Bleomycin. Demethylbleomycin A2 is formed by heating Bleomycin A2. Demethylbleomycin A2 comprises approximately 3.0% of standard grade Bleomycin. Demethylbleomycin A2 has been found to have high antimicrobial activity against Mycobacterium smegmatis compared to Bleomycin A2. Additionally, demethylbleomycin A2 has a lower toxicity profile and greater antitumor properties than Bleomycin A2.
We also offer:
- Bleomycin Sulfate (B005)
- Bleomycin A2 Sulfate, EvoPure® (B019)
- Bleomycin B2 Sulfate, EvoPure® (B020)
|Molecular Formula||C54H81N17O21S3 · xH2SO4|
|CAS Number||11116-31-7 (Bleomycin A2 base)|
|References||Umezawa H (2014) Method for Preparing 3-(methylmercaptol) Propylaminobleomycin. Google Patents. N.p., n.d.|