SKU: D023-2MG

    Demethylbleomycin A2 Sulfate, EvoPure®

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    Demethylbleomycin A2 Sulfate, EvoPure® (Bleomycin impurity D) is a demethylated form of Bleomycin A2 -  a major component in standard grade Bleomycin. Demethylbleomycin A2 is formed by heating Bleomycin A2. Demethylbleomycin A2 comprises approximately 3.0% of standard grade Bleomycin. Demethylbleomycin A2 has been found to have high antimicrobial activity against Mycobacterium smegmatis compared to Bleomycin A2. Additionally, demethylbleomycin A2 has a lower toxicity profile and greater antitumor properties than Bleomycin A2.

    We also offer:

    • Bleomycin Sulfate (B005)
    • Bleomycin A2 Sulfate, EvoPure® (B019)
    • Bleomycin B2 Sulfate, EvoPure® (B020)
    Molecular Formula C54H81N17O21S3 · xH2SO4
    CAS Number 11116-31-7 (Bleomycin A2 base)
    References Umezawa H (2014)  Method for Preparing 3-(methylmercaptol) Propylaminobleomycin. Google Patents. N.p., n.d.