• Demethylbleomycin A2 sulfate packaged and labeled.

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SKU: D023

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Description

Demethylbleomycin A2 sulfate, EvoPure® (bleomycin impurity D) is a demethylated form of bleomycin A2 -  a major component in standard grade bleomycin. Demethylbleomycin A2 is formed by heating bleomycin A2. Demethylbleomycin A2 comprises approximately 3.0% of standard grade bleomycin. Demethylbleomycin A2 has been found to have high antimicrobial activity against Mycobacterium smegmatis compared to bleomycin A2. Additionally, demethylbleomycin A2 has a lower toxicity profile and greater antitumor properties than bleomycin A2.

    Molecular Formula

    C54H81N17O21S3 · xH2SO4

    Molecular Weight

    1400.51 (Free base)

    Tariff Code

    2941.90.1010

Specifications

    Form

    Powder

References

    References

    Umezawa, Hamao. "Method for Preparing 3-(methylmercaptol) Propylaminobleomycin." Google Patents. N.p., n.d. Web. 25 Mar. 2014.

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