Bioactive small molecules are organic compounds that have a low molecular weight (900 daltons). Most pharmaceutical drugs are small molecules. Larger structures such as nucleic acids, proteins, and many polysaccharides are not small molecules.
Rezafungin Acetate (syn: biafungin acetate) is the acetate salt of Rezafungin, a semi-synthetic, next-generation, broad-spectrum echinocandin. It is antifungal agent with activity against Aspergillus, Candida, and Pneumocystis spp. It is a β-glucan...
Oteseconazole is a novel tetrazole that has activity against bacteria causing vulvovaginal candidiasis (RVVC). It is a selective inhibitor of fungal cytochrome P450 enzyme 51 (CYP51). The tetrazole group of Oteseconazole increases its selectivity for...
Levamisole Hydrochloride, USP is the pure levorotatory (L) isomer of Tetramisole. This imidazothiazole is responsible for almost all of the antiparasitic activity of this product. It is a nicotinic acetylcholine receptor agonist. It is more refined than...
Enmetazobactam is a penicillanic acid sulfone extended-spectrum β-lactamase (ESBL) inhibitor. It is an N-methylated tazobactam derivative ideveloped at Orchid Pharma (India) and then out-licensed to Allecra Therapeutics. It has broad-spectrum...
Zoliflodacin is a spiropyrimidinetrione antibiotic belonging to the fluoroquinolone class. It is a bacterial DNA gyrase inhibitor with in vitro antibacterial activity against key Gram-positive, fastidious Gram-negative, atypical bacteria, and anaerobic...
Iodoacetamide is a thiol reagent and can inhibit glycolysis and can be used to study the role of cysteine residues in enzymology. Iodoacetamide is an alkylating reagent for cysteine residues in peptide sequencing, therefore it is useful in...
Gepotidacin is a novel triazaacenaphthylene bacterial type II topoisomerase inhibitor. The compound was developed by GlaxoSmithKline (London, UK) and has broad-spectrum in vitro activity against Gram-positive and Gram-negative bacteria. It has activity...
Danofloxacin is a broad-spectrum antibiotic and third-generation fluoroquinolone class. It was developed by Pfizer and is a synthetic analog of ciprofloxacin. It was introduced in 1991 for pathogens that cause respiratory diseases of bovine, swine and...
Cefetamet Sodium is the sodium salt of Cefetamet, a broad-spectrum third-generation cephalosporin antibiotic. It is classified as a 'aminothiazolyl imimomethoxy cephalosporin' since it has both methyl and...
Cefetamet is a broad-spectrum, third-generation cephalosporin antibiotic. It is classified as a 'aminothiazolyl imimomethoxy cephalosporin' since it has both methyl and [(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side-groups. The...
Tinidazole is a broad-spectrum second-generation 5-nitroimidazole antibiotic and synthetic antiprotozoal agent introduced in 1969. This imidazole derivative is used against bacteria, protozoa and parasites. The compound is similar structurally to...
Ornidazole is a nitroimidazole antibiotic and antiparasitic agent, with broad-spectrum antiprotozoan and anti-aerobic activity. It was synthsized by Hoffmann-La-Roche (1966) and was first introduced for trichomoniasis (Trichomonas vaginalis) in 1974. It...
