7-Oxostaurosporine is the oxidised and highly fluorescent analogue of UCN-01 and UCN-02. 7-Oxostaurosporine is a potent inhibitor of protein kinase C and formation of cellular blebs induced by phorbols. 7-Oxostaurosporine possesses comparable activity against tumor cells lines to UCN-01. Despite its close relationship to UCN-01 and staurosporine, limited access to the metabolite has restricted a more complete investigation of its properties.
7-Oxostaurosporine is soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
7-Oxostaurosporine is soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
