SKU: A093  / 
    CAS Number: 957-68-6

    7-Aminocephalosporanic Acid

    7-aminocephalosporanic acid (7-ACA) is the core chemical structure of cephalosporin antibiotics.
    Application7-Aminocephalosporanic Acid can be used as a starting material to synthesize semi-synthetic cephalosporin antibiotics.
    Mechanism of Action7-Aminocephalosporanic Acid interferes with bacterial cell wall synthesis.
    Molecular FormulaC10H12N2O5S

    Bianchi D, Bortolo R, Golini P, and Cesti P et al (1998)  Enzymatic transformation of Cephalosporin C to 7-ACA by simultaneous action of immobilized D-amino acid oxidase and glutaryl-7-ACA Acylase.   Appl. Biochem. Biotechnol. 73: 257

    Loder B, Newton GGF, and E. P. Abraham EP (1961) The Cephalosporin C nucleus (7-Aminocephalosporanic Acid) and some of its derivatives.  Biochem. J. 79(2):408-416 PMID 13763020

    Morin RB, Jackson BG, Flynn EH and Roeske RW (1962)  Chemistry of cephalosporin antibiotics. 1. 7-Aminocephalosporanic Acid from Cephalosporin C. J. Am. Chem. Soc. 84(17):3400-3401