fabL (yfhR, ygaA) is a gene that encodes enoyl-[acyl-carrier-protein] reductase [NADPH] FabL, a protein that confers resistance to the antibiotic and antimycotic, irgasan/triclosan.
Irgasan (Triclosan) is a broad spectrum antibacterial agent that inhibits bacterial fatty acid synthesis. Irgasan is slightly soluble in water and freely soluble in ethanol and methanol. Mechanism of Action Irgasan demonstrates a...