Quinine Hydrochloride is a naturally occurring alkaloid, and potassium channel blocker. It is a stereoisomer of quinidine which contains an aromatic quinoline and a bicyclic quinuclidine. It was first isolated from the bark of a cinchona tree in 1820.
Quinine Hydrochloride is commonly used in sensory evaluation experiments in food science as a standard for bitterness. In fact, Quinine is the ingredient in tonic water that gives it its bitter taste. Bark extracts have been used to treat malaria since 1632 (Sullivan, 2011) and Quinine was the first compound used to treat malaria (Achan J et al, 2011). Quinine is used as a chiral catalyst backbone.
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