Amodiaquine HCl is an antimalarial 4-aminoquinoline compound with a similar structure and mechanism of action to chloroquine.
|Mechanism of Action||The mechanism of action for amodiaquine is not entirely clear; however, it is thought to inhibit digestion of hemoglobin in malarial parasites.|
|Spectrum||Amodiaquine has a similar spectrum of activity as chloroquine (Plasmodium vivax, Plasmodium malariae) however; it has shown to be more effective against chloroquine resistant Plasmodium falciparum.|
|Molecular Formula||C20H22ClN3O •2HCl •2H2O|
|Impurities||Individual Impurity: ≤0.5% |
Total Impurities: ≤1.0%
|References||Sangkuhl, Katrin. "Amodiaquine Pathway, Pharmacokinetics." PharmGKB. N.p., n.d. Web. 2 Oct. 2013.|