SKU: P102  / 
    CAS Number: 634-97-9

    Pyrrole-2-carboxylic acid

    $43.69 - $152.90
    Pyrrole-2-carboxylic acid is small amphoteric polar metabolite produced by many Streptomyces species, often co-produced with its dimer, pyrocoll. Pyrrole-2-carboxylic acid is an important dereplication standard in discovery, displaying a distinctive UV spectrum and a broad range of biological activities, albeit weak. More recently, pyrrole-2-carboxylic has demonstrated antiparasitic activity against Trypanosomes by selective proline racemase inhibition and has potent antifungal activity against Phytophthora.

    Pyrrole-2-carboxylic acid is soluble in ethanol, methanol, DMF and DMSO.
    ReferencesPyrocoll, an antibiotic, antiparasitic and antitumor compound produced by a novel alkaliphilic Streptomyces strain. Dietera A. et al. J Antibiot. 2003, 56, 639.