• Mycophenolic acid packaged and labeled.

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SKU: M012

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Description

Mycophenolic acid is an immunosuppressant drug commonly used to prevent post-transplant organ rejection. Mycophenolic acid is freely soluble in methanol and insoluble in water.

This product is considered a dangerous good. Quantities above 1 g may be subject to additional shipping fees. Please contact us for specific questions. 

    CAS Number

    24280-93-1

    Molecular Formula

    C17H20O6

    Molecular Weight

    320.34

    Mechanism of Action

    Mycophenolic Acid blocks inosine monophosphate dehydrogenase in the guanosine monophosphate pathway and suppresses cytokine-induced nitric oxide production.

    Storage Conditions

    <30°C

    Tariff Code

    2932.20.2000

Applications

    Cancer Applications

    Mycophenolic acid acts as an inhibitor for inosine monophosphate dehydrogenase (IMPDH), an enzyme responsible for controlling the rate of guanine monophosphate synthesis. IMPDH is required for T-cell and B-cell growth and proliferation to a higher degree than other host cells.

Specifications

    Form

    Powder

    Appearance

    White or off-white powder

    Source

    Penicillium stoloniferum

    Impurity Profile

    Heavy Metals: ≤20ppm
    Total Impurities: ≤2.0%
    Individual Impurity: Not more than 0.5%

    Melting Point

    138-142°C

    Assay

    (On Dried Basis): ≥98.0%

    Loss on Drying

    Not more than 1.0%

    Residue On Ignition

    Not more than 0.1%

Technical Data

Allison, A. C. "Mycophenolate Mofetil and Its Mechanisms of Action."Immunopharmacology 47 (2000): 85-118. Ncbi.gov. May 2000. Web. 11 Sept. 2012.

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