Nicotinamide (Vitamin B3), USP is water-soluble amide form of Nicotinic acid. It is a poly (ADP-ribose) polymerase (PARP) inhibitor, involved in regulation of many cellular processes. It was discovered between 1935 and 1937. Commercially, Nicotonamide is made from nicotinic acid or nicotinonitrile. Structurally, it consists of a pyridine ring to which a primary amide group is attached in the meta position. It shows promise in cell therapy research for diabetes, since it can induce embryonic stem cells into insulin-secreting cells.
Nicotinamide (Vitamin B3), USP conforms to United States Pharmacopeia specifications.
