SKU: N036  / 
    CAS Number: 22862-63-1


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    Neoantimycin is a rare and unusual ring-extended member of the antimycin class. Neoantimycin is produced by a Streptomyces species unrelated to antimycin-producing strains. Literature references to neoantimycin are limited but the recent discovery of the closely related metabolite, prunustatin A, as a selective GRP78 molecular chaperone down-regulator highlights the potential of this class as research probes.

    Neoantimycin is soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.

    Molecular Formula C36H46N2O12
    References Caglioti L (1969)  The structure of neoantimycin.  Tetrahedron. 25:2913

    Umeda Y et al (2005)  Prunustatin A, a novel GRP78 molecular chaperone down-regulator isolated from Streptomyces violaceoniger. J.Antibiot. 58:206