Marcfortine A is an indole alkaloid originally isolated from Penicillin roqueforti. It has nematocidal activity. The marcfortines are structurally related to paraherquamides.
Marcfortine A is soluble in ethanol, methanol, DMF or DMSO but has poor water solubility.
|Mechanism of Action||The marcfortines are thought to act by blocking cholinergic neuromuscular transmission.|
|Insect Biology Applications||Marcfortine A has activity against the gastrointestinal nematode Haemonchus contortus (Zinser et al, 2002).|
|Spectrum||Marcfortines have broad-spectrum anthelmintic activity that includes drug-resistant strains of nematodes.|
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