Itraconazole is an insoluble triazole antifungal agent.
|Mechanism of Action
|Itraconazole increases cell permeability by inhibiting enzymes involved in ergosterol synthesis. The increase of permeability has a toxic effect on the fungi and leads to cell death.
|Itraconazole targets a wide range of fungi Blastomyces, Histoplasma, and Aspergillus.