SKU: E001  / 
    CAS Number: 68797-31-9

    Econazole nitrate

    $58.49 - $556.97

    Econazole nitrate is an insoluble (0.00148 mg/mL) imidazole antifungal that specifically targets the cell membrane of fungi.

    Mechanism of ActionEconazole nitrate increases cell permeability by inhibiting enzymes involved in ergosterol synthesis. The increase of permeability has a toxic effect on the fungi and leads to cell death.
    SpectrumEconazole nitrate targets fungi responsible for tinea (ringworm) especially Trichophyton and Microsporum species.
    Molecular FormulaC18H15Cl3N2O · HNO3

    Rice, Louis B., and Mahmoud A. Ghannoum. "Antifungal Agents: Mode of Action, Mechanisms of Resistance, and Correlation of These Mechanisms with Bacterial Resistance." Clinical Microbiology Reviews (1999): 501-17. Oct. 1999. Web. 22 Aug. 2012.

    Bygrave, F. L., R. Fulceri, and A. Benedetti. "On the Mechanism of Action of Econazole, the Capacitative Calcium Inflow Blocker." PubMed (1998): 75-77. Web. 22 Aug. 2012.