Butyrolactone I is one of a family of three butyrolactones isolated from Aspergillus fumigatus, first reported in 1983. Butyrolactone I is a selective inhibitor of cyclin-dependent kinases CDK1/cyclin B, CDK2 and CDK5, and is an important bioprobe for understanding the cellular roles of CDKs.
Butyrolactone I is soluble in ethanol, methanol, DMF and DMSO.
Butyrolactone I is soluble in ethanol, methanol, DMF and DMSO.
