SKU: R040

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Description
Rifampicin sodium is a bacterial protein synthesis inhibiting antibiotic.

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    CAS Number

    38776-75-9

    Molecular Formula

    C43H58N4NaO12

    Molecular Weight

    845.94

    Mechanism of Action

    Rifampicin targets prokaryotic DNA dependent RNA polymerases which prevent subsequent RNA transcription and protein translation.

    Storage Conditions

    2-8┬░C

    Tariff Code

    2941.90.5000

    Spectrum

    Rifampicin is a broad spectrum antibiotic targeting a wide range of gram positive, gram negative, and Mycobacterium species.

Applications

    Microbiology Applications

    Rifampicin sodium is commonly used in bacterial recombinant protein expression to inhibit bacterial RNA polymerase activity and synthesis of host bacterial proteins. Rifampicin sodium can also be used as a selective agent to isolate Campylobacter jejuni.

References

    References

    "Rifampin: Mechanisms of Action and Resistance." Oxford Journals (1983): n. pag. Clinical Infectious Diseases. Web. 21 Aug. 2012.

    "Philips R., Arnott S.M. and K aplan S.E., 1981, Antibiotics in plant tissue culture: rifampicin effectively controls bacterial contaminants without affecting the growth of short-term explant cultures of Helianthus tuberosus. Plant Science Letters, 21 (1981) 235-240.

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