• Niclosamide anhydrous

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SKU: N048

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Description
Niclosamide is commonly known as an antihelminthic drug used in the treatment of tapeworms. It has also been used as a molluscicide in water treatment, and more recently there are several reports of niclosamide showing anticancer activity. TOKU-E Company offers two forms of niclosamide: Niclosamide anhydrous (N048) and niclosamide monohydrate (N051).

Niclosamide anhydrous is practically insoluble in water. It is sparingly soluble in ethanol, chloroform and ether.

This product is considered a dangerous good. Quantities above 1 g may be subject to additional shipping fees. Please contact us for specific questions.

    CAS Number

    50-65-7

    Molecular Formula

    C13H8Cl2N2O4

    Molecular Weight

    327.12

    Mechanism of Action

    Like other salicylanilides, niclosamide translocates hydrogen into the inner membrane of the mitochondria, uncoupling the oxidative phosphorylation from the electron transport and inhibiting the creation of ATP.

References

    References

    Pan, J.-X., Ding, K., & Wang, C.-Y. (2012). Niclosamide, an old antihelminthic agent, demonstrates antitumor activity by blocking multiple signaling pathways of cancer stem cells. Chinese Journal of Cancer, 31(4), 178–184. http://doi.org/10.5732/cjc.011.10290

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