SKU: C206

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Description
Cecropin B is an antimicrobial peptide originally isolated from insects, but now believed to be naturally produced and found in a large variety of organisms including mammals. It has garnered a lot of interest for its broad-spectrum antiparasitic and antibacterial activities. It is also active against fungi, and has cytotoxic effects on cancer cell lines.

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    CAS Number

    80451-05-4

    Molecular Formula

    C176H301N51O42S

    Molecular Weight

    3835.65

    Mechanism of Action

    The antibacterial mode of action for Cecropins is pore-formation based, in which an antimicrobial peptide inserts itself into the bacterial membrane and allows ions to flow freely through, resulting in cell depolarization and death.

References

    References

    Chen, H. M., Wang, W., Smith, D., & Chan, S. C. (1997). Effects of the anti-bacterial peptide cecropin B and its analogs, cecropins B-1 and B-2, on liposomes, bacteria, and cancer cells. Biochimica Et Biophysica Acta (BBA) - General Subjects, 1336(2), 171-179. doi:10.1016/s0304-4165(97)00024-x

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