2’-C-Methylcytidine (syn: 2CMC) is a viral replication inhibitor, shown to be active against multiple viruses including hepatitis C virus (HCV), inhibiting the HCV NS5B RNA polymerase. It is also used against other viruses including Norwalk, West Nile, dengue, foot-and-mouth, and yellow fever. The compound is a ribonucleoside analog and acts as a bioactive small molecule inhibitor of viral nucleoside polymerase.
2’-C-Methylcytidine is sparingly soluble in water.
