UCN-01 is an indolocarbazole isolated from a high staurosporine-producing Streptomyces culture. UCN-01 enhances the cytotoxicity of other anti-cancer drugs, such as DNA-damaging agents and anti-metabolite drugs, through putative abrogation of G2 and/or S phase accumulation induced by the latter agents.
UCN-01 is soluble in ethanol, methanol, DMF and DMSO.
UCN-01 is soluble in ethanol, methanol, DMF and DMSO.
