Bacterial

Monactin

Monactin is a member of the macrotetrolide complex produced by a range of Streptomyces species. Monactin has not previously been available for intensive investigation. Early literature reported that the related dinactin is a monovalent cation ionophore...

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Elaiophylin

Elaiophylin is a highly characteristic metabolite produced by Streptomyces hygroscopicus. Elaiophylin inhibits testosterone 5-reductase and is synergistic with its co-metabolite, rapamycin, as an antifungal. Elaiophylin also has anthelmintic and...

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Kasugamycin Hydrochloride

Kasugamycin Hydrochloride is a salt form a Kasugamycin, is a broad-spectrum antibacterial and antifungal aminoglycoside originally isolated in 1965 from Streptomyces kasugaensis found near the Kasuga shrine in Japan.  It was discovered by Hamao...

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Spectinomycin Sulfate

Spectinomycin Sulfate is an aminocyclitol antibiotic that is isolated from Streptomyces spectabilis.  Spectinomycin was discovered in culture broth by researchers at the Upjohn Company in 1961. Spectinomycin Sulfate shows activity against...

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Vancomycin Hydrochloride, USP

Vancomycin Hydrochloride, USP (syn: Vancomycin HCl) is a glycopeptide antibiotic derived from Streptomyces orientalis that was discovered in 1953 from a soil sample found in Borneo. It is effective against Gram-positive bacteria such as...

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Novobiocin Sodium

Novobiocin Sodium is an aminocoumarin antibiotic that prevents cell division.  It is an inhibitor of Hsp90 can be used to study heat shock proteins.  It targets Gram-positive organisms, and is commonly used for antimicrobial susceptibility...

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Nonactin

Nonactin is the smallest member of the macrotetrolide complex produced by a range of Streptomyces species. Originally the name, nonactin, reflected the lack of biological activity. The literature is confusing in this respect, as virtually all sources of...

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Gentamicin Sulfate, EP

Gentamicin Sulfate, EP is an aminoglycoside antibiotic complex discovered in 1963 derived from fermentation of Micromonospora purpurea or Micromonospora echinospora. Gentamicin is composed of different components including Gentamicin C complex...

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Tobramycin Sulfate, USP

Tobramycin Sulfate, USP is an aminoglycoside antibiotic derived from Streptomyces tenebrarius. Tobramycin is a member of a broad-spectrum antibiotic complex, nebramycin, that was originally isolated in 1967 by Eli Lilly and Company.  The nebramycin...

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Ticarcillin Disodium, USP

Ticarcillin disodium, USP is an extended-spectrum (4th generation) β-lactam in the carboxypenicillin family. Ticarcillin Disodium (BRL 2288) was originally synthesized by Beecham Research Laboratories in 1967 and was made available for research,...

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Tobramycin, USP

Tobramycin is an aminoglycoside antibiotic derived from Streptomyces tenebrarius. Tobramycin is a member of a broad-spectrum antibiotic complex, nebramycin, that was originally isolated in 1967 by Eli Lilly and Company. The nebramycin complex was...

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Trimethoprim Lactate

Trimethoprim Lactate is a synthetic derivative of trimethoxybenzyl-pyrimidine with bacteriostatic and antiprotozoal properties. As a pyrimidine inhibitor of bacterial dihydrofolate reductase, Trimethoprim binds tightly to the bacterial enzyme, blocking...

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