Gene Selection Antibiotics

G418 Disulfate (Low Endotoxin)

G418 Disulfate (Low Endotoxin) has a strict endotoxin content of ≤ 1 EU/mg. G418 Disulfate, an aminoglycoside antibiotic originally isolated from Micromonospora rhodorangea, is routinely used for gene selection in cell culture. The presence of...

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G418 Disulfate

G418 Disulfate (syn: Geneticin) is an aminoglycoside antibiotic isolated from Micromonospora rhodorangea and is similar in structure to Gentamicin B1.  G418 is an analog of Neomycin Sulfate and has a similar mechanism to Neomycin.  It has a...

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Blasticidin S

Blasticidin S is a peptidyl nucleoside produced by several species of Streptomyces that was first isolated from S. griseochromogenes in 1958.  Blasticidin S inhibits protein synthesis and is active against bacteria, fungi, nematodes, and tumor cells...

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Chloramphenicol Acetate

Chloramphenicol Acetate is the major product of chloramphenicol acetyltransferase, and is a natural co-metabolite of Chloramphenicol with lower potency. It is effective against a wide variety of Gram-positive and Gram-negative bacteria. Chloramphenicol...

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Methotrexate

Methotrexate is a selective agent for dihydrofolate reductase (DHFR)- transfected cells, and a nucleic acid synthesis inhibitor in protein expression systems, thus can be used as an ancillary material in upstream biomanufacturing applications.  It...

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Puromycin Dihydrochloride

Puromycin Dihydrochloride (syn: Puromycin DiHCl) is the hydrochloride salt of Puromycin, an aminonucleoside antibiotic with anti-trypanosomal and anti-neoplastic properties. Puromycin was isolated from Streptomyces alboniger in the 1950s. Puromycin...

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Bleomycin

Bleomycin (Syn: Bleomycin Complex)  is a complex of 11 glycopeptide antibiotics originally isolated from Streptomyces verticillus in 1972. The dominant components are Bleomycin A2 and Bleomycin B2, which typically represent >90% of the total...

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G418 Disulfate ReadyMade™ Solution

G418 Disulfate ReadyMade™ Solution (50 mg/ml in water) is a sterile, aqueous solution of G418 Disulfate.  G418 Disulfate (syn: Geneticin), an aminoglycoside antibiotic originally isolated from Micromonospora rhodorangea. The product is...

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Tetracycline Hydrochloride, EP/USP

Tetracycline Hydrochloride, EP/USP (syn. Tetracycline HCl) is a light-sensitive bacteriostatic polyketide antibiotic frequently used in a wide range of in vitro cell culture applications. Tetracycline (achromycin) is a first-generation tetracycline...

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Spectinomycin Dihydrochloride pentahydrate

Spectinomycin Dihydrochloride pentahydrate is an aminocyclitol antibiotic that is isolated from Streptomyces spectabilis.  Spectinomycin was discovered in culture broth by researchers at the Upjohn company in 1961. Spectinomycin Dihydrochloride...

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Irgasan (Triclosan)

Irgasan (Triclosan) is a broad spectrum antibacterial agent that inhibits bacterial fatty acid synthesis.   Irgasan is slightly soluble in water and freely soluble in ethanol and methanol. Mechanism of Action Irgasan demonstrates a...

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Bleomycin Sulfate, USP

Bleomycin Sulfate, USP is a chemotherapeutic agent and antibiotic commonly used in cancer research. Bleomycin is a mixture of glycopeptide antibiotics Bleomycin A2 and Bleomycin B2 in the ratio of 2:1 accordingly.  The compound is isolated from...

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