Antivirals

Ganciclovir ReadyMade™ Solution

Ganciclovir ReadyMade™ Solution is provided as a sterile-filtered solution formulated in DMSO at a concentration of 2.55 mg/ml. Ganciclovir is an antiviral agent derived from guanine, and is an oxopurine and member of the 2-aminopurines. It is a...

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Nisin ReadyMade™ Solution

Nisin ReadyMade™ Solution is provided as a sterile-filtered solution in 0.02N HCl at a concentration of 20,000-40,000 IU/ml. Nisin is a low molecular weight, natural antibacterial pentacyclic peptide used as a food grade preservative. Nisin is...

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Aureonitol

Aureonitol is a tetrahydrofuran isolated from Chaetomium sp. that acts like a transcriptional regulator for the biosynthesis of other secondary metabolites. The absolute configuration was confirmed in 2008. Aureonitol inhibits influenza A and B virus...

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Remdesivir

Remdesivir is a broad-spectrum antiviral developed by Gilead Sciences. Remdesivir is a prodrug, and upon entry into cells, it is metabolized into the nuceotide triphosphate GS-441524. Remdesivir was investigated for activity for Ebola virus, but it was...

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Methyl Betulinate

Methyl Betulinate is the methyl ester of Betulinic Acid, a pentacyclic lupane terpene isolated as a constituent of various tree species, including birch. In Australia, Methyl Betulinate was isolated from Akania bidwillii (syn. Akania lucens) by Ritchie...

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Mer-NF5003E

Mer-NF5003E is a sesquiterpenoid mycotoxin isolated from Stachybotrys strains, first published in 1994 as an avianmyeloblastosis virus (AMV) protease inhibitor. Mer-NF5003E is inactive against HIV due to host cell toxicity. An analogue, MerNF5003B has...

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Mer-NF5003F

Mer-NF5003F is a sesquiterpenoid mycotoxin isolated from Stachybotrys strains, first published in 1994 as an avianmyeloblastosis virus (AMV) protease inhibitor. Mer-NF5003F is inactive against HIV due to host cell toxicity. An analog, MerNF5003B has been...

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Salazinic Acid

Salazinic Acid is a depsidone lichen metabolite first reported over a 100 years ago and widely distributed across many lichen genera. Salazinic Acid is moderately active against Gram-positive bacteria and some Gram-negative bacteria (P. aeruginosa and S...

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Strychnospermine

Strychnospermine is an alkaloid isolated by Ritchie et al. at the University of Sydney, Australia from the Australian native strychnine tree, Strychnos psilosperma, in 1950. There are no published reports of the biological activity of Strychnospermine. ...

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Seselin

Seselin is a pyranocoumarin isolated from the fruits of Seseli indicum by Spath and colleagues in 1939. Seselin wassubsequently isolated from a number of fruits of diverse species, most notably star anise. More recently, Seselin has beenisolated...

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Stachybotrysin B

Stachybotrysin B is an analogue of a complex of phenylspirodrimanes isolated from the fungus, Stachybotrys chartarum, by collaborating Chinese Key Research Institutes in 2017. Stachybotrysin B is active against HIV but is not cytotoxic.Stachybotrysins...

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Oxysophocarpine

Oxysophocarpine is an alkaloid similar to Matrine (M075) that has recently discovered antiviral activities. In one study it was able to relieve symptoms and reduce mortaility in enterovirus 71-infected mice.Mechanism of ActionThe antiviral mode of action...

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