Antibacterials

Penicolinate B

  Molecular Formula  C23H30N2O4  

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Burnettramic acid A aglycone

Burnettramic acid A and its aglycone are members of a new class of antibiotics from an Australian fungus Aspergillus burnettii.  The rare bolaamphiphilic scaffold consists of β-​d-​mannose linked to a pyrrolizidinedione unit via a 26-​carbon...

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Burnettramic acid A

Burnettramic acid A and its aglycone are members of a new class of antibiotics from an Australian fungus Aspergillus burnettii.  The rare bolaamphiphilic scaffold consists of β-​d-​mannose linked to a pyrrolizidinedione unit via a 26-​carbon...

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D-2-Aminoglutarimide

  Molecular Formula  C5H8N2O2  

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Beauveriolide III

Beauveriolides are 13-membered cyclodepsipeptides isolated from Beauveria sp. Beauveriolide III inhibits acyl-CoA:cholesterol acyltransferase (ACAT) to block the synthesis of cholesteryl ester, leading to a reduction of lipid droplets in macrophages...

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Beauveriolide I

Beauveriolides are 13-membered cyclodepsipeptides isolated from Beauveria sp.. Beauveriolides I and III inhibit macrophage acyl-CoA:cholesterol acyltransferase (ACAT) activity to block the synthesis of cholesteryl ester, leading to a reduction of lipid...

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Beauvericin A

Beauvericin A, a cyclic depsipeptide isolated from serveral fungal genera, notably Fusarium and Beaveria, is the methyl analogue of beauvericin. Beauvericin A is active against mycobacterium and plasmodia. Molecular...

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Avrainvillamide

Avrainvillamide is the monomer of the stephacidin B dimer. Avrainvillamide is active against the proto-oncogene, mutated NPM1, commonly present in patients with acute myeloid lukemia. Avrainvillamide alkylates Cys275 of mutated NPM1, inhibits...

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Avilamycin C

Avilamycin C is a chlorine-containing polysaccharide antibiotic produced by Streptomyces viridochromogenes. Avilamycin is active against Gram-positive bacteria and is used as a growth promotant and for prevention of necrotic enteritis in animals...

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Avilamycin A

Avilamycin A is a chlorine-containing polysaccharide antibiotic produced by Streptomyces viridochromogenes. Avilamycin is active against Gram-positive bacteria and is used as a growth promotant and for prevention of necrotic enteritis in animals...

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Atranorin

Atranorin is a common lichen metabolite that is allergenic and has a broad biological profile, with Anti-inflammatory, analgesic, wound healing, antifungal, antibacterial, antioxidant, antiviral and immunomodulatory. Atranorin has cytotoxic,...

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Aspyrone

Aspyrone is a chiral dihydropyranone with nematocidal activity isolated from Aspergillus melleus by researchers at ICI in 1967. Aspyrone has antifungal and antibacterial activity and is more active than its derivatives or asperlactone. The epoxy group...

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