Antibacterials

Cryptopleurine

Cryptopleurine is a phenanthroquinolizidine secondary metabolite from Cryptocarya pleurosperma first reported by de la Lande, Melbourne University, Australia in 1948 and its structure revised in 1954. Cryptopleurine has antifungal activity via inhibition...

View Details

Creatinine

Creatinine is an endogenous breakdown product of creatine used to measure kidney function. Creatinine has antibacterial activity against Gram-positive and Gram-negative bacteria, including resistant strains. Creatinine may impact the ability of immune...

View Details

Conglobatin B

Conglobatin B was isolated from a previously unreported Streptomyces strain, phylogenetically distinct from the reported conglobatin A producer, Streptomyces conglobatus. Conglobatins B and C diverge from conglobatin through differing...

View Details

Circumdatin A

Circumdatin A, produced by Aspergillus sp., was first reported in 1999 by Rahbaek and colleagues, University of Copenhagen, Denmark. The structure of circumdatin A was revised as a unique oxepine in 2008 using X-ray crystallography. Lack of availability...

View Details

Cinnabarinic acid

Cinnabarinic acid is an endogenous kynurenine metabolite formed from oxidative dimerization of 3-​hydroxyanthranilic acid and transamination of 3-​hydroxykynurenine. Cinnabarinic acid activates glutamate receptors by interacting with residues of the...

View Details

Chaetoviridin A

Chaetoviridin A, an azaphilone isolated from Chaetomium sp., is a potent antifungal against plant pathogenic fungi in vitro and in vivo, suppressing the development of rice blast and wheat leaf rust by over 80​% at a concentration of 62.5 mcg/mL...

View Details

Chaetoglobosin A

Chaetoglobosin A is a mycotoxin of the cytochalasin class produced by Chaetonium globosum. Like other cytochalasins, chaetoglobosin A has a broad biological profile with antitumor, nematocidal, antifungal, antibiotic and antiamebic activity...

View Details

Carbazomycin D

Carbazomycin D is a minor analogue of a family of carbazoles initially isolated from Streptomyces ehimense reported by researchers at Hiroshima University in 1987. Carbazomycin D was identified in a scaled and optimised fermentation of the same strain...

View Details

Carbazomycin C

  Molecular Formula  C16H17NO3  

View Details

Carbazomycin B

Carbazomycin B is the dominant analogue of a family of rare carbazoles initially isolated from an unidentified Streptomyces sp. by researchers at Hiroshima University in 1980. Carbazomycin B is a 5-lipoxygenase inhibitor and free radical scavenger...

View Details

Carbazomycin A

Carbazomycin A is a minor metabolite of a family of rare carbazoles initially isolated from an unidentified Streptomyces sp. (subsequently identified as Streptomyces ehimense) by researchers at Hiroshima University in 1980. Carbazomycin A is active...

View Details

Simvastatin Acid

Simvastatin acid is the active β-hydroxy acid metabolite of simvastatin formed in vivo. Simvastatin acid is a potent inhibitor of 3-hydroxy-3-methylglutarylcoenzyme A (HMG-CoA) reductase, an essential enzyme involved in the in vivo synthesis of...

View Details