Antimicrobials

Ceftiofur Hydrochloride

Ceftiofur Hydrochloride is the hydrochloride salt of Ceftiofur, a broad-spectrum, third-generation β-lactamase resistant cephalosporin commonly used in veterinary research applications that was first described in 1987.  Its metabolite...

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Heronamide C

Heronamide C is an unusual polyene macrocyclic lactam containing two isolated tetraene and triene chromophores. Heronamide C induces a unique reversible vacuolisation of mammalian tumor cells.Heronamide C is soluble in DMF or DMSO. Moderately...

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Diacetylphloroglucinol

Diacetylphloroglucinol (DAPG) is a small molecular weight phenolic metabolite belonging to the phloroglucinol (1,3,5- trihydroxybenzene) family produced by bacteria, including Pseudomonas strains. DAPG exhibits a broad range of biological activities,...

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Demethoxyviridiol

Demethoxyviridiol is a fungal metabolite belonging to the wortmannin and viridin classes. An inhibitor of phosphatidylinositol 3-kinase, demethoxyviridiol affects phospholipid signalling and proliferation of Swiss 3T3 cells.Demethoxyviridiol is soluble...

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Cryptotanshinone

Cryptotanshinone is one of several bioactive tanshinones extracted from the Chinese medicinal herb, Salvia mitiorrhiza. It exhibits a variety of bioactivity including antibacterial, antioxidant and anti-inflammatory effects, but has more recently gained...

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Davercin

Davercin (erythromycin A cyclic 11,12-carbonate) is a first generation semi-synthetic erythromycin. Davercin is prepared by coupling the 11- and 12-OH groups to form a cyclic carbonate. This simple modification improves the stability and hydrophobicity...

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Cyclopiazonic acid

Cyclopiazonic acid is a tremorigenic indole produced by several species of Aspergillus and Penicillium. Cyclopiazonic acid is a highly specific inhibitor of calcium ATPase of sarcoplasmic reticulum, altering calcium homeostasis and ATP-dependent calcium...

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Pristinamycin

Pristinamycin is a streptogramin antibiotic. It is a mixture of Pristinamycin IA (a macrolide) and Pristinamycin IIA (streptogramin A), a depsipeptide). PI and PII are structurally unrelated but synergistic components. They are co-produced naturally in a...

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Virginiamycin B

Virginiamycin B is a depsipeptide antibiotic co-produced with ostreogrycin A, together used as a synergistic mixture. Virginiamycin B, also known as ostreogrycin B and streptogramin B among other synonyms, was discovered independently and named by...

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Teicoplanin A2-2

Teicoplanin A2-2 is a major analog of a family of lipoglycopeptides produced by Actinoplanes teichomyceticus. They possess potent antibiotic activity against Gram-positive bacteria, including MRSA and Enterococcus faecalis. For more Teicoplanin...

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Tetromycin A

Tetromycin A is an unusual tetronic acid, structurally related to kijanimicin, chlorothricin, saccharocarcin, tetrocarcin and versipelostatin. Tetromycin A has pronounced activity against antibiotic susceptible and resistant Gram positive bacteria...

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Virginiamycin

Virginiamycin is a streptogramin, and a mixture of Virginiamycin M1 and Virginiamycin S1.  The commercial mixture is 75% Virginiamycin M1 and 25 % Virginiamycin S1, along with less abundant S analogs.  The two components of the mixture have...

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