Framycetin Sulfate (syn: Neomycin B Sulfate) is the sulfate salt form of Neomycin, a broad-spectrum aminoglycoside antibiotic derived from Streptomyces fradiae. Neomycin B is ~ 65% more active than its stereoisomer, Neomycin C, and ~ 90% more...
Extracellular Death Factor (EDF) is the dramatic name given to an interesting linear pentapeptide produced by E. coli, first identified by Engelberg-Kulka and colleagues in 2007 and published in Science.EDF is soluble in ethanol, methanol, DMF or DMSO...
Erythromycin C (3''-O-demethylerythromycin) is a minor co-metabolite of Erythromycin. Other metabolites include A, B, and D Erythromycin C exhibits a narrower spectrum of antibiotic activity and is less active than A and B. ...
Erythromycin A 9-oxime is a semi-synthetic analog Erythromycin prepared as means of overcoming acid lability and improving oral absorption of Erythromycin A while retaining antibacterial potency. Although not developed as a commercial product,...
Erythromycin A N-oxide is a minor analog of the Erythromycin complex. The N-oxide is a facile metabolite formed in vivo which can revert to Erythromycin A under reducing conditions. Despite its synthetic preparation in the 1950s, the biological...
Flomoxef Sodium is a β-lactam inhibitor and member of the oxacephem family and exhibits antibiotic properties. It has been used for respiratory infections and bone diseases (ie osteoporosis). It was synthesized in 1982 by Shionogi &...
Epichlortetracycline is a degradation product of chlorotetracycline formed by acid-catalysed isomerisation of the dimethylamino group at C4. Epichlortetracycline exhibits little antibiotic activity but its abundance is indicative of poor storage and...
4-Epianhydrochlortetracycline Hydrochloride (chlortetracycline impurity K) is a secondary degradation product formed by dehydration of epichlortetracycline at the C6 position to aromatise the B ring. 4-Epianhydrochlortetracycline is an important standard...
Temocillin Disodium is the disodium salt of Temocillin, a semisynthetic, β-lactamase-resistant carboxypenicillin antimicrobial. Temocillin is the 6-alpha-methoxy derivative of ticarcillin. Temocillin is is used as an alternative to...
Pexiganan is an antimicrobial peptide (AMP) that is effective against a broad spectrum of bacteria including aerobic and anaerobic, gram-positive and gram-negative. Bacterial resistance to pexiganan is very unlikely to develop.Mechanism of...
Dirithromycin is a macrolide antibiotic pro-drug of 9S-erythromycylamine, a close analogue of erythromycin in which the 9-keto group is replaced with an amino group in the S-configuration. Although erythromycylamine overcomes the acid instability of...
Ceftazidime Solubilized is a semi-synthetic, broad-spectrum, third-generation, β-lactam cephalosporin. Patented in 1978, it came into commercial use in 1984. Ceftazidime is bactericidal in action, inhibiting enzymes...
