Antitumor

Lenvatinib

Lenvatinib, the free base form of the compound, is a small-molecule multityrosine kinase inhibitor that inhibits many receptor tyrosine kinases including vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF), and stem cell factor...

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Sandramycin

Sandramycin is a high molecular weight, symmetric, cyclic depsipeptide belonging to the quinomycin class produced by Kribbella sp.. Sandramycin has potent antitumor and antibacterial activity, and is thought to act by bis-intercalation of DNA...

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Roquefortine E

Roquefortine E is an analogue of Roquefortine C, containing an additional isoprenyl unit on the imidazole similar to phenylhistin, a recently described antimitotic agent. Roquefortine E is a selective, albeit weakly active, antitumor agent.Roquefortine E...

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Idelalisib

Idelalisib is the free base version of the compound.  It is a small molecule inhibitor of phosphoinositide 3-kinase.  It also inhibits other class I P13K enzymes.  It also inhibits several signaling pathways, including B-cell receptor...

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Cetyltrimethyl Ammonium Bromide

Cetyltrimethyl Ammonium Bromide (CTAB) has a wide variety of bioactivity. In a laboratory setting, it is favored for the extraction of DNA from plants. CTAB is able to bind to polysaccharides and keep them from affecting the DNA purity. Due to its...

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Reticulol

Reticulol is an isocoumarin metabolite produced by selected species of Streptomyces. Reticulol was first described as a potent inhibitor of cyclic nucleotide phosphodiesterase but more recent research has demonstrated a topoisomerase I inactivation...

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Afatinib

Afatinib is an anilinoquinazoline derivative with a reactive acrylamide group.  It is a tyrosine kinase inhibitor and blocks enzymatically active ErbB (proto-oncogene B of the avian erythroblastosis virus AEV-H strain) receptor family members...

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Rucaparib Camsylate

Rucaparib Camsylate inhibits DNA repair enzyme poly-ADP ribose polymerase-1 (PARP-1), thus it belongs to a class known as PARP inhibitors, which have proven to have anti-cancer activity in a number of cancers.   Rucaparib Camsylate is a...

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Minocycline

Minocycline is a broad-spectrum, second-generation tetracycline. Like other tetracyclines, Minocycline shows broad spectrum antibacterial and antiprotozoan activity. It was patented in 1961 (American cyanamid) and synthesized in 1966 (Lederle Labs)...

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Rucaparib Phosphate

Rucaparib phosphate is the phosphate salt of Rucaparib.  It is a Poly(ADP-ribose) polymerase (PARP) inhibitor.  PARP inhibitors have proven to have anti-cancer activity.Mechanism of ActionPARP inhibitors prevent the synthesis of poly-ADP ribose...

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Rucaparib

Rucaparib inhibits DNA repair enzyme poly-ADP ribose polymerase (PARP), thus it belongs to a class known as PARP inhibitors, which have proven to have anti-cancer activity.  Mechanism of ActionPARP inhibitors prevent the synthesis of poly-ADP...

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Nintedanib Ethanesulfonate

Nintedanib Ethanesulfonate Salt is an organosulfonate salt obtained by combining Nintedanib with one molar equivalent of ethanesulfonic acid.  Nintedanib is an indolinone derivative and small molecule tyrosine-kinase inhibitor, inhibiting...

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