Our products for cancer research include natural products, antibiotics, chemotherapeutic agents, anti-tumor agents, drug precursors, and immunosuppressants. There are hundreds of high quality compounds to choose from to further your discoveries.
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Cyclosporin B, EvoPure is the dihydroxylated metabolite of Cyclosporin A. Cyclosporin B (M-26) and other Cyclosporin metabolites have been found to have lower (<10%) immunosuppressive activity compared Cyclosporin A. Cyclosporin B and...
Streptozocin is an anti-tumor agent and glucosamine-nitrosourea. Streptozocin was discovered in soil microbe Streptomyces achromogenes at Upjohn (now Pfizer). It targets mammalian pancreatic islets beta cells and causes DNA alkylation. ...
Ascomycin is an ethyl analog of FK506 with strong immunosuppressant properties.Mechanism of ActionAscomycin inhibits the production of cytokines produced by Th1 and Th2 cells namely IL-2, IL-4, and IL-10. Additionally, ascomycin inhibits mast cell...
Iodoacetamide is a thiol reagent and can inhibit glycolysis and can be used to study the role of cysteine residues in enzymology. Iodoacetamide is an alkylating reagent for cysteine residues in peptide sequencing, therefore it is useful in proteomics. It...
Rapamycin (Sirolimus) is a natural compound belonging to the macrolide family. It is derived from Streptomyces hygroscopicus isolated from a soil sample from Easter Island in 1972 by Mr. Sehgal of Ayerst Research Labs in Montreal, Quebec...
Colchicine is a classic mitotic inhibitor, disrupting cell division by preventing assembly of microtubules in the mitotic spindle via inhibition of tubulin polymerization. It has pleiotropic effects; It is an anti-inflammatory agent and has been...
Doxorubicin Hydrochloride, USP is an anthracycline antibiotic and 12-hydroxylated version of daunorubicin that inhibits macromolecular biosynthesis through DNA intercalation. This chemotherapeutic compound is used in cancer research for many...
10-Deacetyl Baccatin III (syn: 10-DAB) is a natural organic compound produced by the Pacific Yew tree. It is used as a key backbone intermediate for the semi-synthesis of Paclitaxel (Taxol), an anti-cancer drug and Docetaxel and their analogs. It...
Geldanamycin is a benzoquinone ansamycin antibiotic, which refers to a compound derived from ansamycin, which contain a benzene- or naphthalene-based chromophore linked by an ansa bridge and an amide linkage. Geldanamycin acts as an anti-tumor...
Daunorubicin Hydrochloride, USP (syn: Daunorubicin HCl) is a water soluble anthracycline antibiotic. It is a chemotherapeutic agent produced by Streptomyces coeruleorubidus. It acts as a polymerase inhibitor, and has been found to have...
17-AAG (Tanespimycin; 17-N-Allylamino-17-demethoxygeldanamycin) is a geldanamycin-derived anti-tumor agent currently used in cancer research. It is an inhibitor of heat shock protein 90. The compound epletes cellular STK38/NDR1 and reduces STK38...
Tenuazonic Acid is potent tetramic acid mycotoxin produced by several fungal genera, notably Alternaria. It exhibits antitumor, antiviral and antibacterial activity. It has phytotoxic and phytotoxic properties. It is a compound of interest in...
