Our products for cancer research include natural products, antibiotics, chemotherapeutic agents, anti-tumor agents, drug precursors, and immunosuppressants. There are hundreds of high quality compounds to choose from to further your discoveries.
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Piperafizine A is a methylated diketopiperazine formed by the condensation of phenylalanine, produced by a number of species in the Streptomyces genus. Piperafizine A exhibits little activity in vitro but potentiates vincristine antitumor potency...
Luteoreticulin is a rare nitrophenyl pyranone closely related to aureothin, neoaureothin and its unusual photoisomers SNF4435C and SNF4435D. Metabolites within this class are potent antitumor agents with pronounced immunosuppressive activity, and more...
Quadrone is an unusual sesquiterpene metabolite isolated from Aspergillus terreus and first reported in 1978. Quadrone exhibits antitumor activity but has not been extensively investigated.Quadrone is soluble in ethanol, methanol, DMF and DMSO...
Norfloxacin is a first-generation synthetic fluoroquinolone antibiotic. Mechanism of Action Norfloxacin indirectly inhibits DNA gyrase by binding to nearby DNA substrate. DNA gyrase is an essential DNA replication enzyme which reduces DNA strain...
Rebeccamycin is an indolocarbazole isolated from Lechevalieria aerocolonigenes. Rebeccamycin displays selective antitumor activity against several cell lines. Analogues of rebeccamycin have been tested in clinical trials for cancer therapy.Rebeccamycin...
Miconazole is an imidazole antimycotic compound patented in 1968 by Janssen Pharmaceutica. It inhibits ergosterol synthesis, and a variety of cytochrome P450 enzymes. It can act as a chemopreventive agent in a mammary cancer cell model...
7-Oxostaurosporine is the oxidised and highly fluorescent analogue of UCN-01 and UCN-02. 7-Oxostaurosporine is a potent inhibitor of protein kinase C and formation of cellular blebs induced by phorbols. 7-Oxostaurosporine possesses comparable...
Quinolactacin A1 is the dominant analogue of a family of quinolone metabolites produced by Penicillium citrinum. Quinolactacin A1 rapidly epimerises to equilibrate with its diastereomer quinolactacin A2 in protic solvents. The mixture has been shown to...
Stachybotrylactam is an unusual spirodihydrobenzofuranlactam mycotoxin isolated from a Stachybotrys sp. that has immunosuppressant and weak HIV protease activity. Members of this structural class show diverse activity including antiviral, endothelin and...
Mitomycin C is a bacteriocidal methylazirinopyrroloindoledione antineoplastic antibiotic isolated from Streptomyces spp. Mitomycin C can be used as an inhibitor for cell-free protein biosynthesis research. In addition, Mitomycin C is an efficient...
Stauprimide is a semi-synthetic analogue of the staurosporine family of indolocarbazoles. Stauprimide was first published in 1994 as part of an extensive structure-activity investigation to improve the selective inhibition of protein kinase C as...
Cephalomannine is a diterpene alkaloid compound with antineoplastic properties. Cephalomannine is similar in structure to paclitaxel and can be used as a synthetic material for docetaxel and paclitaxel.Mechanism of ActionCephalomannine is thought to...
