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Oligomycin B is a minor analog of a class of macrocyclic lactones isolated from selected strains of Streptomyces spp. It is a non-selective inhibitor of mitochondrial F1F0 ATP synthase in eukaryotes. Oligomycins exhibit apoptotic cytotoxicity and...
Oligomycin C is a minor analog of a class of macrocyclic lactones isolated from selected strains of Streptomyces spp. It is a non-selective inhibitor of mitochondrial F1F0 ATP synthase in eukaryotes. Oligomycins exhibit apoptotic cytotoxicity...
Tetracycline Hydrochloride, EP/USP (syn. Tetracycline HCl) is a light-sensitive bacteriostatic polyketide antibiotic frequently used in a wide range of in vitro cell culture applications. Tetracycline (achromycin) is a first-generation tetracycline...
Oligomycin D (Rutamycin) is a minor analog of a class of macrocyclic lactones isolated from selected strains of Streptomyces spp. It is a non-selective inhibitor of mitochondrial F1F0 ATP synthase in eukaryotes. Oligomycins exhibit apoptotic...
Pefloxacin Mesylate Dihydrate is a broad-spectrum, synthetic, third-generation fluoroquinolone antibiotic. Pefloxacin, an analog of Norfloxacin, was discovered in 1979. Pefloxacin, like other fluoroquinolones, inhibits bacterial DNA gyrase...
Clotrimazole is a broad-spectrum antifungal belonging to the imidazole subclass of azole compounds. These compounds interfere with the biosynthesis of ergosterol, a major membrane component of the fungal cytoplasmic membrane. Clotrimazole was discovered...
Illudin S is potent antitumor sesquiterpene, first isolated from the fungus, Clitocybe illudens, in 1963. Illudin S is metabolically activated to reactive intermediates that bind DNA. The DNA damage appears to differ from that of other reactive...
Ophiobolin A is the dominant member of a class of phytotoxic metabolites produced by plant pathogenic fungi.Ophiobolin A is soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.Mechanism of ActionOphiobolin A acts by inhibiting calmodulin...
K252A is a staurosporine analogue isolated from a Nocardiopsis strain as a potent inhibitor of protein kinase C. K252A exhibits potent antitumor activity but shows no antimicrobial activity in vitro, or in vivo toxicity in rodents. While K252A is a...
Baicalin is a glycosyloxyflavone isolated from Scutellaria baicalensis Georgi and has demonstrated anti-viral and anti-inflammatory properties. This plant species and its primary constituents including Baicalin were found to have potent inhibitory...
Ophiobolin B is a minor member of a class of phytotoxic metabolites produced by Bipolaris and other genera of plant pathogenic fungi.Ophiobolin B is soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.Mechanism of ActionOphiobolin B acts by...
Salinomycin Sodium (syn: Coxistal, Coxistac) is the sodium salt of Salinomycin, a carboxylic polyether ionophore isolated from Streptomyces albus that has been widely used as an agricultural antibiotic to prevent coccidiosis in poultry. Salinomycin...
