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Deacetylravidomycin (syn: O-Deacetylravidomycin) is the more active and stable analog of the ravidomycin complex produced by Streptomyces ravidus. The metabolite shows potent, light-dependent antitumor activity. Deacetylravidomycin, like the related...
Flumethasone is a topical corticosteroid of the glucocorticoid class used in the treatment of skin disorders where it reduces inflammation.Flumethasone is insoluble in water.Molecular FormulaC22H28F2O5ReferencesAbdel-Aleem, E. A., Hegazy, M. A., Sayed, N...
Ingenol-3-mebutate is an anticancer agent isolated from Euphorbia peplus used in the treatment of Actinic keratosis. Researchers have shown interest in expanding its anticancer activity, finding promise in its ability to promote proapoptotic effects in...
Etoposide is an anticancer topoisomerase inhibitor and semisynthetic epipodophyllotoxin that was derived from the natural product podophyllotoxin extracted from the North American mayapple, Podophyllum peltatum, and the Indian species Podophyllum...
Penigequinolone A is a rare fungal metabolite produced by selected Penicillium species. Penigequinolone A is isolated as an inseparable mixture with its 19-epimer, penigequinolone B. Limited literature cites penigequinolone A as a pollen growth inhibitor...
Prodigiosin is an intensely red pyrrole pigment produced by several bacteria, most notably Serratia marcescens. Prodigiosin has a broad biological profile with activity against fungi, tumor cell lines and malaria. It was shown to be an immunosuppressant...
D-Penicillamine is a copper chelating agent that also functions as a disease-modifying, anti-rheumatic immunosuppressant, and a treatment for cystinuria.TOKU-E offers both D-penicillamine (P107) and L-penicillamine (P112). While they are...
6-(γ,γ-Dimethylallylamino)purine riboside (2-iP riboside) is a cytokinin growth regulator which can be produced endogenously by plants to direct differentiation of callus cells. It is currently being investigated as an emerging anticancer...
Herbimycin C is a minor analogue of the herbimycin complex isolated from Streptomyces hygroscopicus. Herbimycin C possesses potent antitumor activity and converts Rous sarcoma virus-infected rat kidney cells into normal cells. Until now limited access...
Dabrafenib is a selective inhibitor of BRAF, a proto-oncogene. It is primarily used for cancer research to study melanoma. Mechanism of Action Dabrafenib is a reversible and potent adenosine triphosphate-competitive inhibitor that selectively inhibits...
Elaiophylin is a highly characteristic metabolite produced by Streptomyces hygroscopicus. Elaiophylin inhibits testosterone 5-reductase and is synergistic with its co-metabolite, rapamycin, as an antifungal. Elaiophylin also has anthelmintic and...
Epothilone A is a microtubule inhibitor isolated from the myxobacteria, Sorangium cellulosum. Epothilone A has been investigated in clinical trials as an antitumor agent.Epothilone A is soluble in ethanol, methanol, DMF or DMSO. Poor water solubility...