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2-Benzoxazolinone is a metabolite produced by rye (Secale cereale) that inhibits germination and growth and causing oxidative damage. 2-Benzoxazolinone has diverse pharmacological activities including antinociception, anti-inflammatory,...
Spinosyn D, >90% (6-methyl-spinosyn A) is the minor component of Spinosad and makes up to 15% of Spinosad. Spinosyn D differs from Spinosyn A by having a methyl group instead of a hydrogen atom at position C6 on the macrolide. Spinosyn D...
Remdesivir is a broad-spectrum antiviral developed by Gilead Sciences. Remdesivir is a prodrug, and upon entry into cells, it is metabolized into the nuceotide triphosphate GS-441524. Remdesivir was investigated for activity for Ebola virus, but it was...
Baloxavir Marboxil is a synthetic antiviral compound. It has activity against viruses causing influenza A and influenza B. It originated by Shionogi (Japan). It is a small molecule inhibitor of cap-dependent endonuclease found in of influenza A and B...
Pitavastatin Calcium is the calcium salt formulation of Pitavastatin, a lipophilic statin that inhibits cholesterol synthesis and displays cardioprotective properties. Pitavastatin is often combined with zoledronic acid for oncology applications...
Quinine Hydrochloride is a naturally occurring alkaloid, and potassium channel blocker. It is a stereoisomer of quinidine which contains an aromatic quinoline and a bicyclic quinuclidine. It was first isolated from the bark of a cinchona tree in...
Etamsylate (syn: Ethamsylate) is a sulfonic acid derivative and organosulfur compound and haemostatic agent. It increases capillary endothelial resistance and platlet adhesion, and inhibits biosynthesis of prostaglandins. It has...
Sulfachloropyridazine Sodium is the sodium salt of Sulfachloropyridazine, a sulfonamide antibiotic. It has been used to treat the bacteria causing urinary tract infections and is commonly used in aquaculture and animal husbandry. Sulfachloropyridazine...
Pretomanid is a bicyclic nitroimidazole and small molecule pro-drug that is active against actively replicating and hypoxic non-replicating Mycobacterium tuberculosis, the causative agent of tuberculosis (TB). It is activated by deazaflavin-dependent...
Echinocandin B Hydrochloride is the hydrochloride salt of a the natural product and lipopeptide antifungal Ehinocandin B. Discovered in 1974 in Germany, it is the first of its class of antifungals called echinocandins. Echinocandin B is a cyclic...
Pyrantel Citrate is a thiophene and anthelmintic agent. It has been used to characterize Ancylostoma caninum isolates. It was described in 1965 by researchers at Pfizer. Pyrantel and its analogs (oxantel and morantel) are members of the...
Podophyllotoxin, a natural, non-alkaloid toxin lignan extracted from the roots and rhizomes of Podophyllum species, was first isolated in 1880. Serving as a model for antii-tumor properties, Podophyllotoxin has been used to inhibit the growth of various...