• Nisin packaged and labeled.

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SKU: N013

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Description

Nisin (Nisin A) is a bacteriocin polypeptide antibiotic known as a lantibiotic. Nisin is produced by gram-positive bacteria to reduce competitive strain from other gram-positive bacteria.

TOKU-E Company also offers nisin A's natural variant, nisin Z (N055).

    CAS Number

    1414-45-5

    Molecular Formula

    C143H230N42O37S7

    Molecular Weight

    3354.07

    Mechanism of Action

    Nisin is toxic against other gram-positive bacteria by forming pores in the membrane leading to cell death.

    Storage Conditions

    2-8°C

    Tariff Code

    2941.90.1050

    Spectrum

    Nisin is effective against a broad range of gram-positive bacteria and is not toxic to gram-negative cell membranes.

Applications

    Microbiology Applications

    Because of its broad spectrum activity, nisin is commonly used as a food additive to prevent spoilage.

Specifications

    Form

    Powder

    Appearance

    Light brown or creamy colored powder

    Source

    Lactococcus Lactis

    Potency (on a dry basis)

    ≥900 IU/mg

    Loss on Drying

    ≤3.0%

References

    References

    Blackburn, P., and R. J. Evans. "Applications of the Bacteriocin, Nisin." 69.2 (1996): n. pag. www.ncbi.gov. Aplin & Barrett Ltd. and Applied Microbiology Inc. Web. 28 Aug. 2012.

    Ruhl, E., and H. G. Sahl. "Mode of Action of the Peptide Antibiotic Nisin and Influence on the Membrane Potential of Whole Cells and on Cytoplasmic and Artificial Membrane Vesicles." Antimicrobial Agents and Chemotherapy 27.5 (1985): 841-45. www.ncbi.gov. American Society for Microbiology. Web. 28 Aug. 2012.

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