• Nicotinamide (Vitamin B3), USP packaged and labeled.

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SKU: N018

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Description

Nicotinamide is a freely soluble (500 mg/mL) metabolized amide form of vitamin B3.

    CAS Number

    98-92-0

    Molecular Formula

    C6H6N2O

    Molecular Weight

    122.12 g/mol

    Mechanism of Action

    In cells, nicotinamide is converted into NAD (nicotinamide adenine dinucleotide) and NADP (nicotinamide adenine dinucleotide phosphate) which are both involved in redox reactions.

    Storage Conditions

    <30°C

    Tariff Code

    2936.24.0000

Applications

    Cancer Applications

    Nicotinamide has also been used as an anti-cancer agent to inhibit PARP-1, an enzyme responsible for repairing DNA damage caused by chemotherapy treatment.

Specifications

    Form

    Powder

    Appearance

    White crystalline

    Melting Point

    128-131 °C

References

    References

    Ungerstedt, J. S., and et al. "Nicotinamide Is a Potent Inhibitor of Proinflammatory Cytokines." Clinical and Experimental Immunology 131.1 (2003): 48-52.www.ncbi.gov. 7 Jan. 2003. Web. 30 Aug. 2012.

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