• Enramycin B, EvoPure packaged and labeled.

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SKU: E019

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Description

Enramycin (also known as Enduracidin and Enradin) is a polypeptide antibiotic produced by Streptomyces fungicidus and developed as a food additive in Japan. Enramycin is slightly soluble in water and freely soluble in dilute HCl solution. Enramycin is composed of two different compounds: enramycin A and enramycin B.

TOKU-E offers three forms of enramycin: enramycin (E006), enramycin A, EvoPure® (E018), and enramycin B, EvoPure® (E019). EvoPure® products are single antibiotic fractions, most >99% pure.

    CAS Number

    34304-21-7

    Molecular Formula

    C108H140Cl2N26O31

    Molecular Weight

    2369.32

    Mechanism of Action

    Enramycin acts as a MurG inhibitor involved peptidoglycan synthesis in gram positive bacteria. MurG catalyzes the transglycosylation reaction in the last step of peptidoglycan biosynthesis. Inhibition of this step greatly compromises cell wall integrity leading to cell death by lysis.

    Storage Conditions

    -20°C

    Tariff Code

    2941.90.1050

    Spectrum

    Enramycin has a strong antibacterial activity against Gram-positive bacteria and inhibits development of major gut flora pathogens.  Resistance or cross-resistance with existing antibiotics has rarely been observed.

Specifications

    Form

    Powder

    Source

    Semi-synthetic

Technical Data

HPLC, NMR, FTIR, and MS analysis may be available. For more info, please email [email protected].

References

    References

    Fang, Xiao, and et al. "The Mechanism of Action of Ramoplanin and Enduracidin." Royal Society of Chemistry 2 (2006): 69-76. Chem.harvard.edu. Web. 11 Sept. 2012.

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