• Enramycin packaged and labeled.

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SKU: E006

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Description

Enramycin (also known as Enduracidin and Enradin) is a polypeptide antibiotic produced by Streptomyces fungicidus and developed as a food additive in Japan. Enramycin is slightly soluble in water and freely soluble in dilute HCl solution. Enramycin is composed of two different compounds: enramycin A and enramycin B. The ratios of enramycin A to enramycin B varies but is typically ~70:30.

TOKU-E offers three forms of enramycin: enramycin (E006), enramycin A, EvoPure® (E018), and enramycin B, EvoPure® (E019). EvoPure® products are single antibiotic fractions, most >99% pure.

    CAS Number

    11115-82-5

    Molecular Formula

    Enramycin A: C107H138Cl2N26O31
    Enramycin B: C108H140Cl2N26O31

    Molecular Weight

    Enramycin A: 2550.21
    Enramycin B: 2564.24

    Mechanism of Action

    Enramycin acts as a MurG inhibitor involved peptidoglycan synthesis in gram positive bacteria. MurG catalyzes the transglycosylation reaction in the last step of peptidoglycan biosynthesis. Inhibition of this step greatly compromises cell wall integrity leading to cell lysis.

    Storage Conditions

    -20┬░C

    Tariff Code

    2941.90.1050

    Spectrum

    Enramycin has a strong antibacterial activity against Gram-positive bacteria and inhibits development of major gut flora pathogens. Resistance or cross-resistance with existing antibiotics has rarely been observed.

Specifications

    Form

    Powder

    Appearance

    Light Tan Powder

References

    References

    Fang, Xiao, and et al. "The Mechanism of Action of Ramoplanin and Enduracidin." Royal Society of Chemistry 2 (2006): 69-76. Chem.harvard.edu. Web. 11 Sept. 2012.

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