• Enramycin packaged and labeled.

click on thumbnail to zoom
SKU: E006

Size  
Quantity:
  Click 'Bulk Order' for 10 or more
Price: make selection(s)
Description

Enramycin is a polypeptide antibiotic produced by Streptomyces fungicidus and developed as a food additive in Japan. Enramycin is composed of two different compounds: Enramycin A Enramycin B. The ratios of A and B varies but is typically ~70:30. Enramycin is slightly soluble in water and freely soluble in dilute HCl solution.

TOKU-E offers three forms of Enramycin:

  • Enramycin (E006) 
  • Enramycin A, EvoPure® (E018
  • Enramycin B, EvoPure® (E019)

    CAS Number

    11115-82-5

    Molecular Formula

    Enramycin A: C107H138Cl2N26O31
    Enramycin B: C108H140Cl2N26O31

    Molecular Weight

    Enramycin A: 2550.21
    Enramycin B: 2564.24

    Mechanism of Action

    Enramycin acts as a MurG inhibitor involved peptidoglycan synthesis in Gram-positive bacteria. MurG catalyzes the transglycosylation reaction in the last step of peptidoglycan biosynthesis. Inhibition of this step greatly compromises cell wall integrity leading to cell lysis.

    Storage Conditions

    -20┬░C

    Tariff Code

    2941.90.1050

    Spectrum

    Enramycin has a strong antibacterial activity against Gram-positive bacteria and inhibits development of major gut flora pathogens. Resistance or cross-resistance with existing antibiotics has rarely been observed.

Specifications

    Form

    Powder

    Appearance

    light tan powder

    Source

    Streptomyces fungicidus

References

    References

    Fang X et al (2006) The mechanism of action of Ramoplanin and Enduracidin. Royal Soc. Chem. 2: 69-76 PMID 16880924

Other Items In This Category