• Ciprofloxacin packaged and labeled.

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SKU: C031

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Description

Ciprofloxacin is a second generation fluoroquinolone antibiotic.

TOKU-E offers two forms of ciprofloxacin: ciprofloxacin (C031) and ciprofloxacin HCl (C032). Ciprofloxacin is sparingly soluble in aqueous solution (1.1 µg/mL). Ciprofloxacin HCl is freely soluble at 35 mg/mL.

    CAS Number

    85721-33-1

    Molecular Formula

    C17H18FN3O3

    Molecular Weight

    331.34 g/mol

    Mechanism of Action

    Fluoroquinolone antibiotics target bacterial DNA gyrase, an enzyme which reduces DNA strain during replication. Because DNA gyrase is required during DNA replication, subsequent DNA synthesis and cell division is inhibited.

    Storage Conditions

    2-8 ┬░C, protect from light

    Tariff Code

    2933.59.3600

    Spectrum

    Ciprofloxacin is a broad spectrum antibiotic targeting a wide variety of gram positive and gram negative bacteria.

Applications

    Microbiology Applications

    Ciprofloxacin is commonly used in clinical in vitro microbiological antimicrobial susceptibility tests (panels, discs, and MIC strips) against gram positive and gram negative microbial isolates. Medical microbiologists use AST results to recommend antibiotic treatment options for infected patients.

    • For a complete list of ciprofloxacin MIC values, click here.

Specifications

    Form

    Powder

    Appearance

    White or light yellow crystalline powder

    Source

    Synthetic

    Assay

    98.0% - 102.0%

    Loss on Drying

    ≤1.0%

    Residue On Ignition

    ≤0.1%

    Heavy Metals

    ≤20ppm

    Impurities

    Fluoroquinolinic acid: ≤0.2%

References

    References

    Wolfson, John S., and David C. Hooper. "The Fluoroquinolones: Structures, Mechanisms of Action and Resistance, and Spectra of Activity in Vitro." American Society for Microbiology 4th ser. 28 (1985): 581-86.

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