Pirarubicin is an anthracycline anticancer agent, an analogue of doxirubicin that is able to overcome some doxirubicin resistant cell lines.
TOKU-E offers both pirarubicin (P116) and pirarubicin hydrochloride (P117). In aqueous solution, pirarubicin hydrochlloride is soluble in water. Pirarubicin is only slightly soluble in water.
TOKU-E offers both pirarubicin (P116) and pirarubicin hydrochloride (P117). In aqueous solution, pirarubicin hydrochlloride is soluble in water. Pirarubicin is only slightly soluble in water.
Mechanism of Action | Pirarubicin interacts with topoisomerase II, inhibiting the DNA polymerase complex and suppressing DNA replication. |
References | Zhao, H., Yao, Y., Wang, Z., Lin, F., Sun, Y., & Chen, P. (2010). Therapeutic effect of Pirarubicin-Based chemotherapy for Osteosarcoma patients with lung Metastasis. Journal of Chemotherapy, 22(2), 119–124. doi:10.1179/joc.2010.22.2.119 |