SKU: P045  / 
    CAS Number: 33069-62-4

    Paclitaxel (Taxol)


    Paclitaxel is a unique anti-tumor agent derived from the bark of the Pacific Yew tree. Pacitaxel is sparingly soluble in ethanol, DMSO, and DMF.

    Mechanism of ActionPaclitaxel prevents tumor growth by stabilizing microtubules during mitosis in the G2/M growth phase leading to cell death.
    Cancer ApplicationsPaclitaxel can be used to study effects on actively dividing tumor cells.

    Fiser, Andras, et al. "Insights into the Mechanism of Microtubule Stabilization by Taxol." PNAS 103.27 (2006): 10166-0173. Web. 21 June 2013.

    Horwitz, S. B. "Taxol (paclitaxel): Mechanisms of Action." Annals of Oncology 6th ser. 6 (1994): n. pag. Web. 21 June 2013