Fosfomycin Calcium is a broad-spectrum phosphonic acid epoxide antibiotic that inhibits bacterial cell wall synthesis. It is used against bacteria causing urinary tract and intestinal infections and is commonly used in susceptibility testing. It was discovered in Spain in 1969 (Spanish Penicillin and Antibiotics Company) from Streptomyces fradiae but may also be manufactured synthetically. Fosfomycin is a phosphoenolpyruvate analog and has a phosphonic group and an epoxide ring.
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