SKU: E092  / 
    CAS Number: 32483-51-5

    Ethyl Mycophenolate

    $177.00 - $619.00

    Ethyl mycophenolate is the ethyl ester of mycophenolic acid produced by Penicillium brevicompactum but devoid of the antifungal activity of mycophenolic acid. There are few reports of the biological activity of ethyl mycophenolate, however its analogue mycophenolic acid displays antitumor and immunosuppressant effects, among others. Mycophenolic acid acts by inhibiting inosine monophosphate dehydrogenase, controlling the rate of de novo purine synthesis in proliferating B and T lymphocytes.

    Molecular Formula  C19H24O6

    Campbell IM et al (1966)  Some new metabolites related to mycophenolic acid. Tetrahed Lett 7:5107

    Carter SB et al (1969)  Mycophenolic acid: An anti-cancer compound with unusual properties. Nature 223:848

    Nimmesgern E. et al (1996)  Conformational changes and stabilization of inosine 5'-monophosphate dehydrogenase associated with ligand binding and inhibition by mycophenolic acid. J. Biol. Chem. 271:19421