Enramycin A, EvoPure® is a highly purified form of Enramycin A. Enramycin is a polypeptide antibiotic produced by Streptomyces fungicidus and developed as a food additive in Japan. Enramycin is composed of Enramycin A Enramycin B. The ratio of A:B is ~70:30.
Enramycin is slightly soluble in water and freely soluble in dilute HCl solution.
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|Mechanism of Action||Enramycin inhibits transferase enzyme MurG or transflycosylase, which halts peptidoglycan synthesis.|
Enramycin is commonly used in clinical in vitro microbiological antimicrobial susceptibility tests (panels, discs, and MIC strips) against Gram-positive microbial isolates.
|Spectrum||Enramycin is active against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA).|
|References||Kawakami M, Nagai Y, Fujii T and Mitsuhashi S (1971) Anti-microbial activities of Enduracidin (Enramycin) in vitro and in vivo. J. Antibiot. 24(9):583-586|