Cytochalasin E is one of a family of potent mycotoxins produced by a range of fungi. Despite the common mode of action, there is evidence that individual members display diverse selectivity. Specifically, Cytochalasin E acts as an angiogenesis inhibitor and, unlike other cytochalasins, does not inhibit glucose transport. It displays anti-proliferative activity in vitro in endothelial cells. It can inhibit tumor growth and angiogenesis in vivo. It also has antiviral and antimicrobial properties.
Cytochalasin E is soluble in ethanol, methanol, DMF and DMSO.
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