Cytochalasin B is one of the most extensively studied members of a family of potent mycotoxins produced by several species of fungi. All members of the class exhibit profound effects on cytoskeletal proteins, giving rise to pronounced morphogenic activity in animals and plants. Despite the common mode of action, there is evidence that individual members of this class display diverse selectivity. However, lack of comparative co-metabolite analysis has restricted a more complete understanding of their individual selectivity. Cytochalasin B is often used in cytological research, micronucleus assays, lucose transporter studies, characterization of actin polymerization, and cytokinesis studies.
Cytochalasin B is soluble in ethanol, methanol, DMF and DMSO.
