Cisplatin (cis-diammineplatinum(II) dichloride is a potent anti-tumor agent and is active against several types of solid tumors.
This product is considered a dangerous good. Quantities above 1 g may be subject to additional shipping fees. Please contact us for specific questions.
This product is considered a dangerous good. Quantities above 1 g may be subject to additional shipping fees. Please contact us for specific questions.
Mechanism of Action | Cisplatin interacts with DNA and forms intrastrand crosslink adducts which activate anti-tumor proteins ATR, p73, p53, and MAPK. |
Molecular Formula | Cl2H6N2Pt |
References | Siddik, Zahid H. "Cisplatin: Mode of Cytotoxic Action and Molecular Basis of Resistance." Oncogene 22.47 (2003): 7265-279. |